Publications
A
Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments,
Bailey, L. J., Sheehy K. M., Hoey R. J., Schaefer Z. P., Ura M., and Kossiakoff A. A.
, J Immunol Methods, Volume 415, p.24-30, (2014)
Architecture of the fungal nuclear pore inner ring complex.,
Stuwe, Tobias, Bley Christopher J., Thierbach Karsten, Petrovic Stefan, Schilbach Sandra, Mayo Daniel J., Perriches Thibaud, Rundlet Emily J., Jeon Young E., Collins Leslie N., et al.
, Science, 2015 Oct 02, Volume 350, Issue 6256, p.56-64, (2015)
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.,
Marcon, Edyta, Jain Harshika, Bhattacharya Anandi, Guo Hongbo, Phanse Sadhna, Pu Shuye, Byram Gregory, Collins Ben C., Dowdell Evan, Fenner Maria, et al.
, Nat Methods, 2015 Aug, Volume 12, Issue 8, p.725-31, (2015)
B
C
CDR-H3 diversity is not required for antigen recognition by synthetic antibodies,
Persson, H., Ye W., Wernimont A., Adams J. J., Koide A., Koide S., Lam R., and Sidhu S. S.
, J Mol Biol, Volume 425, Number 4, p.803-11, (2013)
Cell biology. New tricks for an old dimer,
Wells, J. A., and Kossiakoff A. A.
, Science, Volume 344, Number 6185, p.703-4, (2014)
Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.,
Ye, Xiaoying, Chan King C., Waters Andrew M., Bess Matthew, Harned Adam, Wei Bih-Rong, Loncarek Jadranka, Luke Brian T., Orsburn Benjamin C., Hollinger Bradley D., et al.
, Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)
Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs.,
Dominik, Pawel K., Borowska Marta T., Dalmas Olivier, Kim Sangwoo S., Perozo Eduardo, Keenan Robert J., and Kossiakoff Anthony A.
, Structure, 2016 Feb 02, Volume 24, Issue 2, p.300-9, (2016)
Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain.,
Huang, Haiming, Kaneko Tomonori, Sidhu Sachdev S., and Li Shawn S. C.
, Methods Mol Biol, 2017, Volume 1555, p.225-254, (2017)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.,
Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al.
, Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)
D
Determination of equilibrium dissociation constants for recombinant antibodies by high-throughput affinity electrophoresis.,
Pan, Yuchen, Sackmann Eric K., Wypisniak Karolina, Hornsby Michael, Datwani Sammy S., and Herr Amy E.
, Sci Rep, 2016 Dec 23, Volume 6, p.39774, (2016)
Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.,
Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al.
, Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)
Direct Proximity Tagging of Small Molecule Protein Targets Using an Engineered NEDD8 Ligase.,
Hill, Zachary B., Pollock Samuel B., Zhuang Min, and Wells James A.
, J Am Chem Soc, 2016 Oct 12, Volume 138, Issue 40, p.13123-13126, (2016)
E
Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.,
Mukherjee, Somnath, Griffin Dionne H., Horn James R., Rizk Shahir S., Nocula-Lugowska Malgorzata, Malmqvist Magnus, Kim Sangwoo S., and Kossiakoff Anthony A.
, J Biol Chem, 2018 02 23, Volume 293, Issue 8, p.2815-2828, (2018)
An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.,
Slezak, Tomasz, Bailey Lucas J., Jaskolowski Mateusz, Nahotko Dominik A., Filippova Ekaterina V., Davydova Elena K., and Kossiakoff Anthony A.
, Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)
Engineered ultra-high affinity synthetic antibodies for SARS-CoV-2 neutralization and detection.,
Slezak, Tomasz, and Kossiakoff Anthony A.
, J Mol Biol, 2021 Mar 25, p.166956, (2021)
Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling,
Rizk, S. S., Kouadio J. L., Szymborska A., Duguid E. M., Mukherjee S., Zheng J., Clevenger C. V., and Kossiakoff A. A.
, Cell Commun Signal, 01/2015, Volume 13, Number 1, p.1, (2015)
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.,
Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al.
, Elife, 03/2018, Volume 7, (2018)
F
Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds.,
Liu, Hongyan, Saxena Abhishek, Sidhu Sachdev S., and Wu Donghui
, Front Immunol, 2017, Volume 8, p.38, (2017)
G
Generating Conformation and Complex-Specific Synthetic Antibodies.,
Paduch, Marcin, and Kossiakoff Anthony A.
, Methods Mol Biol, 2017, Volume 1575, p.93-119, (2017)
Generating conformation-specific synthetic antibodies to trap proteins in selected functional states,
Paduch, M., Koide A., Uysal S., Rizk S. S., Koide S., and Kossiakoff A. A.
, Methods, Volume 60, Number 1, p.3-14, (2013)
H
A High Through-put Platform for Recombinant Antibodies to Folded Proteins.,
Hornsby, Michael, Paduch Marcin, Miersch Shane, Sääf Annika, Matsuguchi Tet, Lee Brian, Wypisniak Karolina, Doak Allison, King Daniel, Usatyuk Svitlana, et al.
, Mol Cell Proteomics, 2015 Oct, Volume 14, Issue 10, p.2833-47, (2015)
A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents.,
Leung, Isabel, Jarvik Nick, and Sidhu Sachdev S.
, J Mol Biol, 2017 01 06, Volume 429, Issue 1, p.115-127, (2017)
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.,
Pollock, Samuel B., Hu Amy, Mou Yun, Martinko Alexander J., Julien Olivier, Hornsby Michael, Ploder Lynda, Adams Jarrett J., Geng Huimin, Müschen Markus, et al.
, Proc Natl Acad Sci U S A, 2018 03 13, Volume 115, Issue 11, p.2836-2841, (2018)
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation,
Marcon, E., Ni Z., Pu S., Turinsky A. L., Trimble S. S., Olsen J. B., Silverman-Gavrila R., Silverman-Gavrila L., Phanse S., Guo H., et al.
, Cell Rep, Volume 8, Number 1, p.297-310, (2014)
Pages
RAN Publications
Latest publications
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Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. (published on 2021 Jul 14)
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K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle. (published on 2021 Jul 08)
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A T cell redirection platform for co-targeting dual antigens on solid tumors. (published on 2021 Jan-Dec)