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Filters: Keyword is Protein Conformation [Clear All Filters]

2021

Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins., Bloch, Joël S., Mukherjee Somnath, Kowal Julia, Filippova Ekaterina V., Niederer Martina, Pardon Els, Steyaert Jan, Kossiakoff Anthony A., and Locher Kaspar P. , Proc Natl Acad Sci U S A, 2021 Nov 23, Volume 118, Issue 47, (2021)

Structure of an AMPK complex in an inactive, ATP-bound state., Yan, Yan, Mukherjee Somnath, Harikumar Kaleeckal G., Strutzenberg Timothy S., X Zhou Edward, Suino-Powell Kelly, Xu Ting-Hai, Sheldon Ryan D., Lamp Jared, Brunzelle Joseph S., et al. , Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)

Structures of ABCB4 provide insight into phosphatidylcholine translocation., Nosol, Kamil, Bang-Sørensen Rose, Irobalieva Rossitza N., Erramilli Satchal K., Stieger Bruno, Kossiakoff Anthony A., and Locher Kaspar P. , Proc Natl Acad Sci U S A, 2021 Aug 17, Volume 118, Issue 33, (2021)

2020

An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability., Slezak, Tomasz, Bailey Lucas J., Jaskolowski Mateusz, Nahotko Dominik A., Filippova Ekaterina V., Davydova Elena K., and Kossiakoff Anthony A. , Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)

Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., Mukherjee, Somnath, Erramilli Satchal K., Ammirati Mark, Alvarez Frances J. D., Fennell Kimberly F., Purdy Michael D., Skrobek Blazej M., Radziwon Katarzyna, Coukos John, Kang Yanyong, et al. , Nat Commun, March 27 2020, Volume 11, Issue 1, p.1598, (2020)

2018

Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins., Mukherjee, Somnath, Griffin Dionne H., Horn James R., Rizk Shahir S., Nocula-Lugowska Malgorzata, Malmqvist Magnus, Kim Sangwoo S., and Kossiakoff Anthony A. , J Biol Chem, 2018 02 23, Volume 293, Issue 8, p.2815-2828, (2018)

Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme., Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al. , Elife, 03/2018, Volume 7, (2018)

Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination., Bailey, Lucas J., Sheehy Kimberly M., Dominik Pawel K., Liang Wenguang G., Rui Huan, Clark Michael, Jaskolowski Mateusz, Kim Yejoon, Deneka Dawid, Tang Wei-Jen, et al. , J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)

2017

Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain., Huang, Haiming, Kaneko Tomonori, Sidhu Sachdev S., and Li Shawn S. C. , Methods Mol Biol, 2017, Volume 1555, p.225-254, (2017)

2016

Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs., Dominik, Pawel K., Borowska Marta T., Dalmas Olivier, Kim Sangwoo S., Perozo Eduardo, Keenan Robert J., and Kossiakoff Anthony A. , Structure, 2016 Feb 02, Volume 24, Issue 2, p.300-9, (2016)

A polar ring endows improved specificity to an antibody fragment., Schaefer, Zachary P., Bailey Lucas J., and Kossiakoff Anthony A. , Protein Sci, 2016 07, Volume 25, Issue 7, p.1290-8, (2016)

Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment., Shao, Yaming, Huang Hao, Qin Daoming, Li Nan-Sheng, Koide Akiko, Staley Jonathan P., Koide Shohei, Kossiakoff Anthony A., and Piccirilli Joseph A. , J Mol Biol, 2016 10 09, Volume 428, Issue 20, p.4100-4114, (2016)

2015

An improved single-chain Fab platform for efficient display and recombinant expression., Koerber, James T., Hornsby Michael J., and Wells James A. , J Mol Biol, 2015 Jan 30, Volume 427, Issue 2, p.576-86, (2015)

A switchable yeast display/secretion system., Van Deventer, James A., Kelly Ryan L., Rajan Saravanan, K Wittrup Dane, and Sidhu Sachdev S. , Protein Eng Des Sel, 2015 Oct, Volume 28, Issue 10, p.317-25, (2015)