Publications

Found 39 results
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2023
Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA., Erramilli, Satchal K., Dominik Pawel K., Deneka Dawid, Tokarz Piotr, Kim Sangwoo S., Reddy Bharat G., Skrobek Blazej M., Dalmas Olivier, Perozo Eduardo, and Kossiakoff Anthony A. , J Mol Biol, 2023 Jul 01, Volume 435, Issue 17, p.168192, (2023)
Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA., Erramilli, Satchal K., Dominik Pawel K., Deneka Dawid, Tokarz Piotr, Kim Sangwoo S., Reddy Bharat G., Skrobek Blazej M., Dalmas Olivier, Perozo Eduardo, and Kossiakoff Anthony A. , J Mol Biol, 2023 Jul 01, Volume 435, Issue 17, p.168192, (2023)
Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA., Erramilli, Satchal K., Dominik Pawel K., Deneka Dawid, Tokarz Piotr, Kim Sangwoo S., Reddy Bharat G., Skrobek Blazej M., Dalmas Olivier, Perozo Eduardo, and Kossiakoff Anthony A. , J Mol Biol, 2023 Jul 01, Volume 435, Issue 17, p.168192, (2023)
Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder., Kordon, Szymon P., Dutka Przemysław, Adamska Justyna M., Bandekar Sumit J., Leon Katherine, Erramilli Satchal K., Adams Brock, Li Jingxian, Kossiakoff Anthony A., and Araç Demet , Nat Commun, 2023 Feb 06, Volume 14, Issue 1, p.635, (2023)
Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase., Bloch, Joël S., John Alan, Mao Runyu, Mukherjee Somnath, Boilevin Jérémy, Irobalieva Rossitza N., Darbre Tamis, Scott Nichollas E., Reymond Jean-Louis, Kossiakoff Anthony A., et al. , Nat Chem Biol, 2023 Jan 05, (2023)
2022
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes., Orlando, Benjamin J., Dominik Pawel K., Roy Sourav, Ogbu Chinemerem P., Erramilli Satchal K., Kossiakoff Anthony A., and Vecchio Alex J. , J Biol Chem, 2022 Sep, Volume 298, Issue 9, p.102357, (2022)
Quaternary structure independent folding of voltage-gated ion channel pore domain subunits., Arrigoni, Cristina, Lolicato Marco, Shaya David, Rohaim Ahmed, Findeisen Felix, Fong Lam-Kiu, Colleran Claire M., Dominik Pawel, Kim Sangwoo S., Schuermann Jonathan P., et al. , Nat Struct Mol Biol, 2022 Jun, Volume 29, Issue 6, p.537-548, (2022)
Quaternary structure independent folding of voltage-gated ion channel pore domain subunits., Arrigoni, Cristina, Lolicato Marco, Shaya David, Rohaim Ahmed, Findeisen Felix, Fong Lam-Kiu, Colleran Claire M., Dominik Pawel, Kim Sangwoo S., Schuermann Jonathan P., et al. , Nat Struct Mol Biol, 2022 Jun, Volume 29, Issue 6, p.537-548, (2022)
Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias., Yen, Yu-Chen, Schafer Christopher T., Gustavsson Martin, Eberle Stefanie A., Dominik Pawel K., Deneka Dawid, Zhang Penglie, Schall Thomas J., Kossiakoff Anthony A., Tesmer John J. G., et al. , Sci Adv, 2022 Jul 15, Volume 8, Issue 28, p.eabn8063, (2022)
Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias., Yen, Yu-Chen, Schafer Christopher T., Gustavsson Martin, Eberle Stefanie A., Dominik Pawel K., Deneka Dawid, Zhang Penglie, Schall Thomas J., Kossiakoff Anthony A., Tesmer John J. G., et al. , Sci Adv, 2022 Jul 15, Volume 8, Issue 28, p.eabn8063, (2022)
2020
An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability., Slezak, Tomasz, Bailey Lucas J., Jaskolowski Mateusz, Nahotko Dominik A., Filippova Ekaterina V., Davydova Elena K., and Kossiakoff Anthony A. , Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)
Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment., Lokareddy, Ravi K., Ko Ying Hui, Hong Nathaniel, Doll Steven G., Paduch Marcin, Niederweis Michael, Kossiakoff Anthony A., and Cingolani Gino , Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)
Structure and mechanism of the ER-based glucosyltransferase ALG6., Bloch, Joël S., Pesciullesi Giorgio, Boilevin Jérémy, Nosol Kamil, Irobalieva Rossitza N., Darbre Tamis, Aebi Markus, Kossiakoff Anthony A., Reymond Jean-Louis, and Locher Kaspar P. , Nature, 03/2020, Volume 579, Issue 7799, p.443-447, (2020)
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., Mukherjee, Somnath, Erramilli Satchal K., Ammirati Mark, Alvarez Frances J. D., Fennell Kimberly F., Purdy Michael D., Skrobek Blazej M., Radziwon Katarzyna, Coukos John, Kang Yanyong, et al. , Nat Commun, March 27 2020, Volume 11, Issue 1, p.1598, (2020)
2019
Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM., Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al. , Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)
Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM., Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al. , Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT., Kim, Jonathan, Tan Yong Zi, Wicht Kathryn J., Erramilli Satchal K., Dhingra Satish K., Okombo John, Vendome Jeremie, Hagenah Laura M., Giacometti Sabrina I., Warren Audrey L., et al. , Nature, 2019 12, Volume 576, Issue 7786, p.315-320, (2019)
2018
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme., Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al. , Elife, 03/2018, Volume 7, (2018)
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme., Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al. , Elife, 03/2018, Volume 7, (2018)
Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination., Bailey, Lucas J., Sheehy Kimberly M., Dominik Pawel K., Liang Wenguang G., Rui Huan, Clark Michael, Jaskolowski Mateusz, Kim Yejoon, Deneka Dawid, Tang Wei-Jen, et al. , J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)
Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination., Bailey, Lucas J., Sheehy Kimberly M., Dominik Pawel K., Liang Wenguang G., Rui Huan, Clark Michael, Jaskolowski Mateusz, Kim Yejoon, Deneka Dawid, Tang Wei-Jen, et al. , J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)
Structural basis for activation of voltage sensor domains in an ion channel TPC1., Kintzer, Alexander F., Green Evan M., Dominik Pawel K., Bridges Michael, Armache Jean-Paul, Deneka Dawid, Kim Sangwoo S., Hubbell Wayne, Kossiakoff Anthony A., Cheng Yifan, et al. , Proc Natl Acad Sci U S A, 2018 09 25, Volume 115, Issue 39, p.E9095-E9104, (2018)
Structural basis for activation of voltage sensor domains in an ion channel TPC1., Kintzer, Alexander F., Green Evan M., Dominik Pawel K., Bridges Michael, Armache Jean-Paul, Deneka Dawid, Kim Sangwoo S., Hubbell Wayne, Kossiakoff Anthony A., Cheng Yifan, et al. , Proc Natl Acad Sci U S A, 2018 09 25, Volume 115, Issue 39, p.E9095-E9104, (2018)

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RAN Publications

University of Toronto  UCSF  The University of Chicago  QB3  Chicago Biomedical Consortium