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2021

Structural basis of omega-3 fatty acid transport across the blood-brain barrier., Cater, Rosemary J., Chua Geok Lin, Erramilli Satchal K., Keener James E., Choy Brendon C., Tokarz Piotr, Chin Cheen Fei, Q Y Quek Debra, Kloss Brian, Pepe Joseph G., et al. , Nature, 2021 Jun 16, (2021)

Structural basis of omega-3 fatty acid transport across the blood-brain barrier., Cater, Rosemary J., Chua Geok Lin, Erramilli Satchal K., Keener James E., Choy Brendon C., Tokarz Piotr, Chin Cheen Fei, Q Y Quek Debra, Kloss Brian, Pepe Joseph G., et al. , Nature, 2021 Jun 16, (2021)

Structural basis of omega-3 fatty acid transport across the blood-brain barrier., Cater, Rosemary J., Chua Geok Lin, Erramilli Satchal K., Keener James E., Choy Brendon C., Tokarz Piotr, Chin Cheen Fei, Q Y Quek Debra, Kloss Brian, Pepe Joseph G., et al. , Nature, 2021 Jun 16, (2021)

Structure of an AMPK complex in an inactive, ATP-bound state., Yan, Yan, Mukherjee Somnath, Harikumar Kaleeckal G., Strutzenberg Timothy S., X Zhou Edward, Suino-Powell Kelly, Xu Ting-Hai, Sheldon Ryan D., Lamp Jared, Brunzelle Joseph S., et al. , Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)

Structures of ABCB4 provide insight into phosphatidylcholine translocation., Nosol, Kamil, Bang-Sørensen Rose, Irobalieva Rossitza N., Erramilli Satchal K., Stieger Bruno, Kossiakoff Anthony A., and Locher Kaspar P. , Proc Natl Acad Sci U S A, 2021 Aug 17, Volume 118, Issue 33, (2021)

Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1., Chen, Qiuyan, Plasencia Manolo, Li Zhuang, Mukherjee Somnath, Patra Dhabaleswar, Chen Chun-Liang, Klose Thomas, Yao Xin-Qiu, Kossiakoff Anthony A., Chang Leifu, et al. , Nature, 2021 Jul 14, (2021)

Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1., Chen, Qiuyan, Plasencia Manolo, Li Zhuang, Mukherjee Somnath, Patra Dhabaleswar, Chen Chun-Liang, Klose Thomas, Yao Xin-Qiu, Kossiakoff Anthony A., Chang Leifu, et al. , Nature, 2021 Jul 14, (2021)

A T cell redirection platform for co-targeting dual antigens on solid tumors., Enderle, Leonie, Shalaby Karim H., Gorelik Maryna, Weiss Alexander, Blazer Levi L., Paduch Marcin, Cardarelli Lia, Kossiakoff Anthony, Adams Jarrett J., and Sidhu Sachdev S. , MAbs, 2021 Jan-Dec, Volume 13, Issue 1, p.1933690, (2021)

2020

An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability., Slezak, Tomasz, Bailey Lucas J., Jaskolowski Mateusz, Nahotko Dominik A., Filippova Ekaterina V., Davydova Elena K., and Kossiakoff Anthony A. , Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)

Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment., Lokareddy, Ravi K., Ko Ying Hui, Hong Nathaniel, Doll Steven G., Paduch Marcin, Niederweis Michael, Kossiakoff Anthony A., and Cingolani Gino , Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)

Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment., Lokareddy, Ravi K., Ko Ying Hui, Hong Nathaniel, Doll Steven G., Paduch Marcin, Niederweis Michael, Kossiakoff Anthony A., and Cingolani Gino , Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)

Structure and mechanism of the ER-based glucosyltransferase ALG6., Bloch, Joël S., Pesciullesi Giorgio, Boilevin Jérémy, Nosol Kamil, Irobalieva Rossitza N., Darbre Tamis, Aebi Markus, Kossiakoff Anthony A., Reymond Jean-Louis, and Locher Kaspar P. , Nature, 03/2020, Volume 579, Issue 7799, p.443-447, (2020)

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling., Tsutsumi, Naotaka, Mukherjee Somnath, Waghray Deepa, Janda Claudia Y., Jude Kevin M., Miao Yi, Burg John S., Aduri Nanda Gowtham, Kossiakoff Anthony A., Gati Cornelius, et al. , Elife, August 7 2020, Volume 9, (2020)

Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., Mukherjee, Somnath, Erramilli Satchal K., Ammirati Mark, Alvarez Frances J. D., Fennell Kimberly F., Purdy Michael D., Skrobek Blazej M., Radziwon Katarzyna, Coukos John, Kang Yanyong, et al. , Nat Commun, March 27 2020, Volume 11, Issue 1, p.1598, (2020)

Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., Mukherjee, Somnath, Erramilli Satchal K., Ammirati Mark, Alvarez Frances J. D., Fennell Kimberly F., Purdy Michael D., Skrobek Blazej M., Radziwon Katarzyna, Coukos John, Kang Yanyong, et al. , Nat Commun, March 27 2020, Volume 11, Issue 1, p.1598, (2020)

2019

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM., Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al. , Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM., Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al. , Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)

Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin., Farcasanu, Mara, Wang Andrew G., Uchański Tomasz, Bailey Lucas J., Yue Jiping, Chen Zhaochun, Wu Xiaoyang, Kossiakoff Anthony, and Tang Wei-Jen , Biochemistry, 2019 07 09, Volume 58, Issue 27, p.2996-3004, (2019)

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT., Kim, Jonathan, Tan Yong Zi, Wicht Kathryn J., Erramilli Satchal K., Dhingra Satish K., Okombo John, Vendome Jeremie, Hagenah Laura M., Giacometti Sabrina I., Warren Audrey L., et al. , Nature, 2019 12, Volume 576, Issue 7786, p.315-320, (2019)

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT., Kim, Jonathan, Tan Yong Zi, Wicht Kathryn J., Erramilli Satchal K., Dhingra Satish K., Okombo John, Vendome Jeremie, Hagenah Laura M., Giacometti Sabrina I., Warren Audrey L., et al. , Nature, 2019 12, Volume 576, Issue 7786, p.315-320, (2019)

2018

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)

Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins., Mukherjee, Somnath, Griffin Dionne H., Horn James R., Rizk Shahir S., Nocula-Lugowska Malgorzata, Malmqvist Magnus, Kim Sangwoo S., and Kossiakoff Anthony A. , J Biol Chem, 2018 02 23, Volume 293, Issue 8, p.2815-2828, (2018)

Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins., Mukherjee, Somnath, Griffin Dionne H., Horn James R., Rizk Shahir S., Nocula-Lugowska Malgorzata, Malmqvist Magnus, Kim Sangwoo S., and Kossiakoff Anthony A. , J Biol Chem, 2018 02 23, Volume 293, Issue 8, p.2815-2828, (2018)

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