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2023

Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels., Kern, David M., Bleier Julia, Mukherjee Somnath, Hill Jennifer M., Kossiakoff Anthony A., Isacoff Ehud Y., and Brohawn Stephen G. , Nat Struct Mol Biol, 2023 Mar 16, (2023)

Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase., Bloch, Joël S., John Alan, Mao Runyu, Mukherjee Somnath, Boilevin Jérémy, Irobalieva Rossitza N., Darbre Tamis, Scott Nichollas E., Reymond Jean-Louis, Kossiakoff Anthony A., et al. , Nat Chem Biol, 2023 Jan 05, (2023)

Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase., Bloch, Joël S., John Alan, Mao Runyu, Mukherjee Somnath, Boilevin Jérémy, Irobalieva Rossitza N., Darbre Tamis, Scott Nichollas E., Reymond Jean-Louis, Kossiakoff Anthony A., et al. , Nat Chem Biol, 2023 Jan 05, (2023)

2022

Quaternary structure independent folding of voltage-gated ion channel pore domain subunits., Arrigoni, Cristina, Lolicato Marco, Shaya David, Rohaim Ahmed, Findeisen Felix, Fong Lam-Kiu, Colleran Claire M., Dominik Pawel, Kim Sangwoo S., Schuermann Jonathan P., et al. , Nat Struct Mol Biol, 2022 Jun, Volume 29, Issue 6, p.537-548, (2022)

Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver., Liu, Hongtao, Irobalieva Rossitza N., Bang-Sørensen Rose, Nosol Kamil, Mukherjee Somnath, Agrawal Parth, Stieger Bruno, Kossiakoff Anthony A., and Locher Kaspar P. , Cell Res, 2022 Aug, Volume 32, Issue 8, p.773-776, (2022)

Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins., Ura, Marcin, Mukherjee Somnath, Marcon Edyta, Koestler Stefan A., and Kossiakoff Anthony A. , J Mol Biol, 2022 Jun 30, Volume 434, Issue 12, p.167602, (2022)

Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins., Ura, Marcin, Mukherjee Somnath, Marcon Edyta, Koestler Stefan A., and Kossiakoff Anthony A. , J Mol Biol, 2022 Jun 30, Volume 434, Issue 12, p.167602, (2022)

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers., Lim, Shion A., Zhou Jie, Martinko Alexander J., Wang Yung-Hua, Filippova Ekaterina V., Steri Veronica, Wang Donghui, Remesh Soumya G., Liu Jia, Hann Byron, et al. , J Clin Invest, 2022 Feb 15, Volume 132, Issue 4, (2022)

2021

Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins., Bloch, Joël S., Mukherjee Somnath, Kowal Julia, Filippova Ekaterina V., Niederer Martina, Pardon Els, Steyaert Jan, Kossiakoff Anthony A., and Locher Kaspar P. , Proc Natl Acad Sci U S A, 2021 Nov 23, Volume 118, Issue 47, (2021)

Structural basis of omega-3 fatty acid transport across the blood-brain barrier., Cater, Rosemary J., Chua Geok Lin, Erramilli Satchal K., Keener James E., Choy Brendon C., Tokarz Piotr, Chin Cheen Fei, Q Y Quek Debra, Kloss Brian, Pepe Joseph G., et al. , Nature, 2021 Jun 16, (2021)

Structural basis of omega-3 fatty acid transport across the blood-brain barrier., Cater, Rosemary J., Chua Geok Lin, Erramilli Satchal K., Keener James E., Choy Brendon C., Tokarz Piotr, Chin Cheen Fei, Q Y Quek Debra, Kloss Brian, Pepe Joseph G., et al. , Nature, 2021 Jun 16, (2021)

Structure of an AMPK complex in an inactive, ATP-bound state., Yan, Yan, Mukherjee Somnath, Harikumar Kaleeckal G., Strutzenberg Timothy S., X Zhou Edward, Suino-Powell Kelly, Xu Ting-Hai, Sheldon Ryan D., Lamp Jared, Brunzelle Joseph S., et al. , Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)

Structure of an AMPK complex in an inactive, ATP-bound state., Yan, Yan, Mukherjee Somnath, Harikumar Kaleeckal G., Strutzenberg Timothy S., X Zhou Edward, Suino-Powell Kelly, Xu Ting-Hai, Sheldon Ryan D., Lamp Jared, Brunzelle Joseph S., et al. , Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)

Structure of an AMPK complex in an inactive, ATP-bound state., Yan, Yan, Mukherjee Somnath, Harikumar Kaleeckal G., Strutzenberg Timothy S., X Zhou Edward, Suino-Powell Kelly, Xu Ting-Hai, Sheldon Ryan D., Lamp Jared, Brunzelle Joseph S., et al. , Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)

Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1., Chen, Qiuyan, Plasencia Manolo, Li Zhuang, Mukherjee Somnath, Patra Dhabaleswar, Chen Chun-Liang, Klose Thomas, Yao Xin-Qiu, Kossiakoff Anthony A., Chang Leifu, et al. , Nature, 2021 Jul 14, (2021)

2020

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling., Tsutsumi, Naotaka, Mukherjee Somnath, Waghray Deepa, Janda Claudia Y., Jude Kevin M., Miao Yi, Burg John S., Aduri Nanda Gowtham, Kossiakoff Anthony A., Gati Cornelius, et al. , Elife, August 7 2020, Volume 9, (2020)

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling., Tsutsumi, Naotaka, Mukherjee Somnath, Waghray Deepa, Janda Claudia Y., Jude Kevin M., Miao Yi, Burg John S., Aduri Nanda Gowtham, Kossiakoff Anthony A., Gati Cornelius, et al. , Elife, August 7 2020, Volume 9, (2020)

Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., Mukherjee, Somnath, Erramilli Satchal K., Ammirati Mark, Alvarez Frances J. D., Fennell Kimberly F., Purdy Michael D., Skrobek Blazej M., Radziwon Katarzyna, Coukos John, Kang Yanyong, et al. , Nat Commun, March 27 2020, Volume 11, Issue 1, p.1598, (2020)

2019

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM., Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al. , Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM., Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al. , Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT., Kim, Jonathan, Tan Yong Zi, Wicht Kathryn J., Erramilli Satchal K., Dhingra Satish K., Okombo John, Vendome Jeremie, Hagenah Laura M., Giacometti Sabrina I., Warren Audrey L., et al. , Nature, 2019 12, Volume 576, Issue 7786, p.315-320, (2019)

2018

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)

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