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Visualization of arrestin recruitment by a G-protein-coupled receptor, Shukla, A. K., Westfield G. H., Xiao K., Reis R. I., Huang L. Y., Tripathi-Shukla P., Qian J., Li S., Blanc A., Oleskie A. N., et al. , Nature, Volume 512, Number 7513, p.218-22, (2014)

T

Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody., Rizk, Shahir S., Mukherjee Somnath, Koide Akiko, Koide Shohei, and Kossiakoff Anthony A. , Sci Rep, 2017 04 03, Volume 7, Issue 1, p.556, (2017)

A T cell redirection platform for co-targeting dual antigens on solid tumors., Enderle, Leonie, Shalaby Karim H., Gorelik Maryna, Weiss Alexander, Blazer Levi L., Paduch Marcin, Cardarelli Lia, Kossiakoff Anthony, Adams Jarrett J., and Sidhu Sachdev S. , MAbs, 2021 Jan-Dec, Volume 13, Issue 1, p.1933690, (2021)

S

A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of gamma-secretase, Zhang, X., Hoey R., Koide A., Dolios G., Paduch M., Nguyen P., Wu X., Li Y., Wagner S. L., Wang R., et al. , J Biol Chem, Volume 289, Number 50, p.34851-61, (2014)

Synthetic antibodies and peptides recognizing progressive multifocal leukoencephalopathy-specific point mutations in polyomavirus JC capsid viral protein 1., Chen, Gang, Gorelik Leonid, Simon Kenneth J., Pavlenco Alevtina, Cheung Anne, Brickelmaier Margot, Chen Ling Ling, Jin Ping, Weinreb Paul H., and Sidhu Sachdev S. , MAbs, 2015, Volume 7, Issue 4, p.681-92, (2015)

Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., Mukherjee, Somnath, Erramilli Satchal K., Ammirati Mark, Alvarez Frances J. D., Fennell Kimberly F., Purdy Michael D., Skrobek Blazej M., Radziwon Katarzyna, Coukos John, Kang Yanyong, et al. , Nat Commun, March 27 2020, Volume 11, Issue 1, p.1598, (2020)

A switchable yeast display/secretion system., Van Deventer, James A., Kelly Ryan L., Rajan Saravanan, K Wittrup Dane, and Sidhu Sachdev S. , Protein Eng Des Sel, 2015 Oct, Volume 28, Issue 10, p.317-25, (2015)

Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo, Rizk, S. S., Misiura A., Paduch M., and Kossiakoff A. A. , Bioconjug Chem, Volume 23, Number 1, p.42-6, (2012)

Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1., Chen, Qiuyan, Plasencia Manolo, Li Zhuang, Mukherjee Somnath, Patra Dhabaleswar, Chen Chun-Liang, Klose Thomas, Yao Xin-Qiu, Kossiakoff Anthony A., Chang Leifu, et al. , Nature, 2021 Jul 14, (2021)

The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab., Radwańska, Malwina J., Jaskółowski Mateusz, Davydova Elena, Derewenda Urszula, Miyake Tsuyoshi, Engel Daniel A., Kossiakoff Anthony A., and Derewenda Zygmunt S. , Acta Crystallogr D Struct Biol, 2018 07 01, Volume 74, Issue Pt 7, p.681-689, (2018)

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling., Tsutsumi, Naotaka, Mukherjee Somnath, Waghray Deepa, Janda Claudia Y., Jude Kevin M., Miao Yi, Burg John S., Aduri Nanda Gowtham, Kossiakoff Anthony A., Gati Cornelius, et al. , Elife, August 7 2020, Volume 9, (2020)

Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide, Shukla, A. K., Manglik A., Kruse A. C., Xiao K., Reis R. I., Tseng W. C., Staus D. P., Hilger D., Uysal S., Huang L. Y., et al. , Nature, Volume 497, Number 7447, p.137-41, (2013)

Structure and mechanism of the ER-based glucosyltransferase ALG6., Bloch, Joël S., Pesciullesi Giorgio, Boilevin Jérémy, Nosol Kamil, Irobalieva Rossitza N., Darbre Tamis, Aebi Markus, Kossiakoff Anthony A., Reymond Jean-Louis, and Locher Kaspar P. , Nature, 03/2020, Volume 579, Issue 7799, p.443-447, (2020)

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT., Kim, Jonathan, Tan Yong Zi, Wicht Kathryn J., Erramilli Satchal K., Dhingra Satish K., Okombo John, Vendome Jeremie, Hagenah Laura M., Giacometti Sabrina I., Warren Audrey L., et al. , Nature, 2019 12, Volume 576, Issue 7786, p.315-320, (2019)

Structural Modeling of Human Growth Hormone Receptor using Computational Simulations and NMR Spectroscopy, Rui, H., Kossiakoff A., and Im W. , Biophys J, Volume 104, Number 2, Supplement 1, p.117a-118a, (2013)

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain, Li, Q., Wanderling S., Paduch M., Medovoy D., Singharoy A., McGreevy R., Villalba-Galea C. A., Hulse R. E., Roux B., Schulten K., et al. , Nat Struct Mol Biol, Volume 21, Number 3, p.244-52, (2014)

Structural basis of omega-3 fatty acid transport across the blood-brain barrier., Cater, Rosemary J., Chua Geok Lin, Erramilli Satchal K., Keener James E., Choy Brendon C., Tokarz Piotr, Chin Cheen Fei, Q Y Quek Debra, Kloss Brian, Pepe Joseph G., et al. , Nature, 2021 Jun 16, (2021)

Structural basis for activation of voltage sensor domains in an ion channel TPC1., Kintzer, Alexander F., Green Evan M., Dominik Pawel K., Bridges Michael, Armache Jean-Paul, Deneka Dawid, Kim Sangwoo S., Hubbell Wayne, Kossiakoff Anthony A., Cheng Yifan, et al. , Proc Natl Acad Sci U S A, 2018 09 25, Volume 115, Issue 39, p.E9095-E9104, (2018)

Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2., Sun, Jian, Paduch Marcin, Kim Sang-Ah, Kramer Ryan M., Barrios Adam F., Lu Vincent, Luke Judy, Usatyuk Svitlana, Kossiakoff Anthony A., and Tan Song , Proc Natl Acad Sci U S A, 2018 10 02, Volume 115, Issue 40, p.10010-10015, (2018)

Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment., Shao, Yaming, Huang Hao, Qin Daoming, Li Nan-Sheng, Koide Akiko, Staley Jonathan P., Koide Shohei, Kossiakoff Anthony A., and Piccirilli Joseph A. , J Mol Biol, 2016 10 09, Volume 428, Issue 20, p.4100-4114, (2016)

Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display., Huang, Haiming, Economopoulos Nicolas O., Liu Bernard A., Uetrecht Andrea, Gu Jun, Jarvik Nick, Nadeem Vincent, Pawson Tony, Moffat Jason, Miersch Shane, et al. , Protein Sci, 2015 Nov, Volume 24, Issue 11, p.1890-900, (2015)

Scalable high throughput selection from phage-displayed synthetic antibody libraries, Miersch, S., Li Z., Hanna R., McLaughlin M. E., Hornsby M., Matsuguchi T., Paduch M., Saaf A., Wells J., Koide S., et al. , J Vis Exp, 01/2015, Number 95, p.51492, (2015)

R

Redox-based reagents for chemoselective methionine bioconjugation., Lin, Shixian, Yang Xiaoyu, Jia Shang, Weeks Amy M., Hornsby Michael, Lee Peter S., Nichiporuk Rita V., Iavarone Anthony T., Wells James A., F Toste Dean, et al. , Science, 2017 02 10, Volume 355, Issue 6325, p.597-602, (2017)

Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment., Lokareddy, Ravi K., Ko Ying Hui, Hong Nathaniel, Doll Steven G., Paduch Marcin, Niederweis Michael, Kossiakoff Anthony A., and Cingolani Gino , Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)

Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin., Farcasanu, Mara, Wang Andrew G., Uchański Tomasz, Bailey Lucas J., Yue Jiping, Chen Zhaochun, Wu Xiaoyang, Kossiakoff Anthony, and Tang Wei-Jen , Biochemistry, 2019 07 09, Volume 58, Issue 27, p.2996-3004, (2019)

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