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Filters: Author is Kossiakoff, Anthony A and Keyword is Humans [Clear All Filters]

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A

Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation., Marcon, Edyta, Jain Harshika, Bhattacharya Anandi, Guo Hongbo, Phanse Sadhna, Pu Shuye, Byram Gregory, Collins Ben C., Dowdell Evan, Fenner Maria, et al. , Nat Methods, 2015 Aug, Volume 12, Issue 8, p.725-31, (2015)

C

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein., Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al. , Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)

D

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM., Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al. , Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)

Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes., Orlando, Benjamin J., Dominik Pawel K., Roy Sourav, Ogbu Chinemerem P., Erramilli Satchal K., Kossiakoff Anthony A., and Vecchio Alex J. , J Biol Chem, 2022 Sep, Volume 298, Issue 9, p.102357, (2022)

E

An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability., Slezak, Tomasz, Bailey Lucas J., Jaskolowski Mateusz, Nahotko Dominik A., Filippova Ekaterina V., Davydova Elena K., and Kossiakoff Anthony A. , Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)

Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme., Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al. , Elife, 03/2018, Volume 7, (2018)

G

Generating Conformation and Complex-Specific Synthetic Antibodies., Paduch, Marcin, and Kossiakoff Anthony A. , Methods Mol Biol, 2017, Volume 1575, p.93-119, (2017)

L

Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination., Bailey, Lucas J., Sheehy Kimberly M., Dominik Pawel K., Liang Wenguang G., Rui Huan, Clark Michael, Jaskolowski Mateusz, Kim Yejoon, Deneka Dawid, Tang Wei-Jen, et al. , J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)

O

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins., Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al. , PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)

P

A polar ring endows improved specificity to an antibody fragment., Schaefer, Zachary P., Bailey Lucas J., and Kossiakoff Anthony A. , Protein Sci, 2016 07, Volume 25, Issue 7, p.1290-8, (2016)

Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity., Sundaram, Karthik M., Zhang Yilin, Mitra Anirban K., Kouadio Jean-Louis K., Gwin Katja, Kossiakoff Anthony A., Roman Brian B., Lengyel Ernst, and Piccirilli Joseph A. , Cancer Res, 2017 Apr 01, Volume 77, Issue 7, p.1684-1696, (2017)

S

Structure of an AMPK complex in an inactive, ATP-bound state., Yan, Yan, Mukherjee Somnath, Harikumar Kaleeckal G., Strutzenberg Timothy S., X Zhou Edward, Suino-Powell Kelly, Xu Ting-Hai, Sheldon Ryan D., Lamp Jared, Brunzelle Joseph S., et al. , Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)

Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver., Liu, Hongtao, Irobalieva Rossitza N., Bang-Sørensen Rose, Nosol Kamil, Mukherjee Somnath, Agrawal Parth, Stieger Bruno, Kossiakoff Anthony A., and Locher Kaspar P. , Cell Res, 2022 Aug, Volume 32, Issue 8, p.773-776, (2022)

The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab., Radwańska, Malwina J., Jaskółowski Mateusz, Davydova Elena, Derewenda Urszula, Miyake Tsuyoshi, Engel Daniel A., Kossiakoff Anthony A., and Derewenda Zygmunt S. , Acta Crystallogr D Struct Biol, 2018 07 01, Volume 74, Issue Pt 7, p.681-689, (2018)

Structures of ABCB4 provide insight into phosphatidylcholine translocation., Nosol, Kamil, Bang-Sørensen Rose, Irobalieva Rossitza N., Erramilli Satchal K., Stieger Bruno, Kossiakoff Anthony A., and Locher Kaspar P. , Proc Natl Acad Sci U S A, 2021 Aug 17, Volume 118, Issue 33, (2021)

Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., Mukherjee, Somnath, Erramilli Satchal K., Ammirati Mark, Alvarez Frances J. D., Fennell Kimberly F., Purdy Michael D., Skrobek Blazej M., Radziwon Katarzyna, Coukos John, Kang Yanyong, et al. , Nat Commun, March 27 2020, Volume 11, Issue 1, p.1598, (2020)

Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins., Ura, Marcin, Mukherjee Somnath, Marcon Edyta, Koestler Stefan A., and Kossiakoff Anthony A. , J Mol Biol, 2022 Jun 30, Volume 434, Issue 12, p.167602, (2022)

T

Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody., Rizk, Shahir S., Mukherjee Somnath, Koide Akiko, Koide Shohei, and Kossiakoff Anthony A. , Sci Rep, 2017 04 03, Volume 7, Issue 1, p.556, (2017)

Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers., Lim, Shion A., Zhou Jie, Martinko Alexander J., Wang Yung-Hua, Filippova Ekaterina V., Steri Veronica, Wang Donghui, Remesh Soumya G., Liu Jia, Hann Byron, et al. , J Clin Invest, 2022 Feb 15, Volume 132, Issue 4, (2022)