Publications
A
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.,
Marcon, Edyta, Jain Harshika, Bhattacharya Anandi, Guo Hongbo, Phanse Sadhna, Pu Shuye, Byram Gregory, Collins Ben C., Dowdell Evan, Fenner Maria, et al.
, Nat Methods, 2015 Aug, Volume 12, Issue 8, p.725-31, (2015)
C
Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain.,
Huang, Haiming, Kaneko Tomonori, Sidhu Sachdev S., and Li Shawn S. C.
, Methods Mol Biol, 2017, Volume 1555, p.225-254, (2017)
F
Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds.,
Liu, Hongyan, Saxena Abhishek, Sidhu Sachdev S., and Wu Donghui
, Front Immunol, 2017, Volume 8, p.38, (2017)
H
A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents.,
Leung, Isabel, Jarvik Nick, and Sidhu Sachdev S.
, J Mol Biol, 2017 01 06, Volume 429, Issue 1, p.115-127, (2017)
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.,
Pollock, Samuel B., Hu Amy, Mou Yun, Martinko Alexander J., Julien Olivier, Hornsby Michael, Ploder Lynda, Adams Jarrett J., Geng Huimin, Müschen Markus, et al.
, Proc Natl Acad Sci U S A, 2018 03 13, Volume 115, Issue 11, p.2836-2841, (2018)
I
Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins.,
Gallo, Eugenio, Kelil Abdellali, Haughey Michael, Cazares-Olivera Mariana, Yates Bradley P., Zhang Mingjun, Wang Nai-Yu, Blazer Levi, Carderelli Lia, Adams Jarrett J., et al.
, J Mol Biol, 2021 Jun 04, Volume 433, Issue 15, p.167090, (2021)
O
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.,
Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al.
, PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)
S
Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display.,
Huang, Haiming, Economopoulos Nicolas O., Liu Bernard A., Uetrecht Andrea, Gu Jun, Jarvik Nick, Nadeem Vincent, Pawson Tony, Moffat Jason, Miersch Shane, et al.
, Protein Sci, 2015 Nov, Volume 24, Issue 11, p.1890-900, (2015)
A switchable yeast display/secretion system.,
Van Deventer, James A., Kelly Ryan L., Rajan Saravanan, K Wittrup Dane, and Sidhu Sachdev S.
, Protein Eng Des Sel, 2015 Oct, Volume 28, Issue 10, p.317-25, (2015)
Synthetic antibodies and peptides recognizing progressive multifocal leukoencephalopathy-specific point mutations in polyomavirus JC capsid viral protein 1.,
Chen, Gang, Gorelik Leonid, Simon Kenneth J., Pavlenco Alevtina, Cheung Anne, Brickelmaier Margot, Chen Ling Ling, Jin Ping, Weinreb Paul H., and Sidhu Sachdev S.
, MAbs, 2015, Volume 7, Issue 4, p.681-92, (2015)
T
A T cell redirection platform for co-targeting dual antigens on solid tumors.,
Enderle, Leonie, Shalaby Karim H., Gorelik Maryna, Weiss Alexander, Blazer Levi L., Paduch Marcin, Cardarelli Lia, Kossiakoff Anthony, Adams Jarrett J., and Sidhu Sachdev S.
, MAbs, 2021 Jan-Dec, Volume 13, Issue 1, p.1933690, (2021)
Publications
- Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.
- Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
- Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
- Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
- Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
- Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
- Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.
- Structure of an AMPK complex in an inactive, ATP-bound state.
- Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.
- Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
- Structures of ABCB4 provide insight into phosphatidylcholine translocation.
- Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
- Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.
- Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.