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S

Structural basis for activation of voltage sensor domains in an ion channel TPC1., Kintzer, Alexander F., Green Evan M., Dominik Pawel K., Bridges Michael, Armache Jean-Paul, Deneka Dawid, Kim Sangwoo S., Hubbell Wayne, Kossiakoff Anthony A., Cheng Yifan, et al. , Proc Natl Acad Sci U S A, 2018 09 25, Volume 115, Issue 39, p.E9095-E9104, (2018)

Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2., Sun, Jian, Paduch Marcin, Kim Sang-Ah, Kramer Ryan M., Barrios Adam F., Lu Vincent, Luke Judy, Usatyuk Svitlana, Kossiakoff Anthony A., and Tan Song , Proc Natl Acad Sci U S A, 2018 10 02, Volume 115, Issue 40, p.10010-10015, (2018)

Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment., Shao, Yaming, Huang Hao, Qin Daoming, Li Nan-Sheng, Koide Akiko, Staley Jonathan P., Koide Shohei, Kossiakoff Anthony A., and Piccirilli Joseph A. , J Mol Biol, 2016 10 09, Volume 428, Issue 20, p.4100-4114, (2016)

Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display., Huang, Haiming, Economopoulos Nicolas O., Liu Bernard A., Uetrecht Andrea, Gu Jun, Jarvik Nick, Nadeem Vincent, Pawson Tony, Moffat Jason, Miersch Shane, et al. , Protein Sci, 2015 Nov, Volume 24, Issue 11, p.1890-900, (2015)

Scalable high throughput selection from phage-displayed synthetic antibody libraries, Miersch, S., Li Z., Hanna R., McLaughlin M. E., Hornsby M., Matsuguchi T., Paduch M., Saaf A., Wells J., Koide S., et al. , J Vis Exp, 01/2015, Number 95, p.51492, (2015)

R

Redox-based reagents for chemoselective methionine bioconjugation., Lin, Shixian, Yang Xiaoyu, Jia Shang, Weeks Amy M., Hornsby Michael, Lee Peter S., Nichiporuk Rita V., Iavarone Anthony T., Wells James A., F Toste Dean, et al. , Science, 2017 02 10, Volume 355, Issue 6325, p.597-602, (2017)

Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment., Lokareddy, Ravi K., Ko Ying Hui, Hong Nathaniel, Doll Steven G., Paduch Marcin, Niederweis Michael, Kossiakoff Anthony A., and Cingolani Gino , Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)

Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin., Farcasanu, Mara, Wang Andrew G., Uchański Tomasz, Bailey Lucas J., Yue Jiping, Chen Zhaochun, Wu Xiaoyang, Kossiakoff Anthony, and Tang Wei-Jen , Biochemistry, 2019 07 09, Volume 58, Issue 27, p.2996-3004, (2019)

Q

Quaternary structure independent folding of voltage-gated ion channel pore domain subunits., Arrigoni, Cristina, Lolicato Marco, Shaya David, Rohaim Ahmed, Findeisen Felix, Fong Lam-Kiu, Colleran Claire M., Dominik Pawel, Kim Sangwoo S., Schuermann Jonathan P., et al. , Nat Struct Mol Biol, 2022 Jun, Volume 29, Issue 6, p.537-548, (2022)

P

Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo, Mateja, A., Paduch M., Chang H. Y., Szydlowska A., Kossiakoff A. A., Hegde R. S., and Keenan R. J. , Science, 03/2015, Volume 347, Number 6226, p.1152-5, (2015)

Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity., Sundaram, Karthik M., Zhang Yilin, Mitra Anirban K., Kouadio Jean-Louis K., Gwin Katja, Kossiakoff Anthony A., Roman Brian B., Lengyel Ernst, and Piccirilli Joseph A. , Cancer Res, 2017 Apr 01, Volume 77, Issue 7, p.1684-1696, (2017)

Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies, Welch, B. D., Paduch M., Leser G. P., Bergman Z., Kors C. A., Paterson R. G., Jardetzky T. S., Kossiakoff A. A., and Lamb R. A. , J Virol, Volume 88, Number 20, p.11713-25, (2014)

The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical., Galilee, Meytal, Britan-Rosich Elena, Griner Sarah L., Uysal Serdar, Baumgärtel Viola, Lamb Don C., Kossiakoff Anthony A., Kotler Moshe, Stroud Robert M., Marx Ailie, et al. , Structure, 2016 11 01, Volume 24, Issue 11, p.1936-1946, (2016)

A polar ring endows improved specificity to an antibody fragment., Schaefer, Zachary P., Bailey Lucas J., and Kossiakoff Anthony A. , Protein Sci, 2016 07, Volume 25, Issue 7, p.1290-8, (2016)

O

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins., Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al. , PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)

N

Nuclear pores. Architecture of the nuclear pore complex coat, Stuwe, T., Correia A. R., Lin D. H., Paduch M., Lu V. T., Kossiakoff A. A., and Hoelz A. , Science, 03/2015, Volume 347, Number 6226, p.1148-52, (2015)

L

Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination., Bailey, Lucas J., Sheehy Kimberly M., Dominik Pawel K., Liang Wenguang G., Rui Huan, Clark Michael, Jaskolowski Mateusz, Kim Yejoon, Deneka Dawid, Tang Wei-Jen, et al. , J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)

K

K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle., Yu, Yuanyuan, Zheng Qingyun, Erramilli Satchal K., Pan Man, Park Seongjin, Xie Yuan, Li Jingxian, Fei Jingyi, Kossiakoff Anthony A., Liu Lei, et al. , Nat Chem Biol, 2021 Jul 08, (2021)

I

Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder., Kordon, Szymon P., Dutka Przemysław, Adamska Justyna M., Bandekar Sumit J., Leon Katherine, Erramilli Satchal K., Adams Brock, Li Jingxian, Kossiakoff Anthony A., and Araç Demet , Nat Commun, 2023 Feb 06, Volume 14, Issue 1, p.635, (2023)

Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins., Gallo, Eugenio, Kelil Abdellali, Haughey Michael, Cazares-Olivera Mariana, Yates Bradley P., Zhang Mingjun, Wang Nai-Yu, Blazer Levi, Carderelli Lia, Adams Jarrett J., et al. , J Mol Biol, 2021 Jun 04, Volume 433, Issue 15, p.167090, (2021)

An improved single-chain Fab platform for efficient display and recombinant expression., Koerber, James T., Hornsby Michael J., and Wells James A. , J Mol Biol, 2015 Jan 30, Volume 427, Issue 2, p.576-86, (2015)

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of gamma-secretase using synthetic antibodies, Zhang, X., Hoey R. J., Lin G., Koide A., Leung B., Ahn K., Dolios G., Paduch M., Ikeuchi T., Wang R., et al. , Proc Natl Acad Sci U S A, Volume 109, Number 22, p.8534-9, (2012)

H

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation, Marcon, E., Ni Z., Pu S., Turinsky A. L., Trimble S. S., Olsen J. B., Silverman-Gavrila R., Silverman-Gavrila L., Phanse S., Guo H., et al. , Cell Rep, Volume 8, Number 1, p.297-310, (2014)

Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies., Pollock, Samuel B., Hu Amy, Mou Yun, Martinko Alexander J., Julien Olivier, Hornsby Michael, Ploder Lynda, Adams Jarrett J., Geng Huimin, Müschen Markus, et al. , Proc Natl Acad Sci U S A, 2018 03 13, Volume 115, Issue 11, p.2836-2841, (2018)

A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents., Leung, Isabel, Jarvik Nick, and Sidhu Sachdev S. , J Mol Biol, 2017 01 06, Volume 429, Issue 1, p.115-127, (2017)

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