Publications
S
A polar ring endows improved specificity to an antibody fragment.,
Schaefer, Zachary P., Bailey Lucas J., and Kossiakoff Anthony A.
, Protein Sci, 2016 07, Volume 25, Issue 7, p.1290-8, (2016)
Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.,
Shao, Yaming, Huang Hao, Qin Daoming, Li Nan-Sheng, Koide Akiko, Staley Jonathan P., Koide Shohei, Kossiakoff Anthony A., and Piccirilli Joseph A.
, J Mol Biol, 2016 10 09, Volume 428, Issue 20, p.4100-4114, (2016)
Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide,
Shukla, A. K., Manglik A., Kruse A. C., Xiao K., Reis R. I., Tseng W. C., Staus D. P., Hilger D., Uysal S., Huang L. Y., et al.
, Nature, Volume 497, Number 7447, p.137-41, (2013)
Visualization of arrestin recruitment by a G-protein-coupled receptor,
Shukla, A. K., Westfield G. H., Xiao K., Reis R. I., Huang L. Y., Tripathi-Shukla P., Qian J., Li S., Blanc A., Oleskie A. N., et al.
, Nature, Volume 512, Number 7513, p.218-22, (2014)
An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.,
Slezak, Tomasz, Bailey Lucas J., Jaskolowski Mateusz, Nahotko Dominik A., Filippova Ekaterina V., Davydova Elena K., and Kossiakoff Anthony A.
, Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)
Engineered ultra-high affinity synthetic antibodies for SARS-CoV-2 neutralization and detection.,
Slezak, Tomasz, and Kossiakoff Anthony A.
, J Mol Biol, 2021 Mar 25, p.166956, (2021)
Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.,
Srinivasan, Karthik, Erramilli Satchal K., Chakravarthy Srinivas, Gonzalez Adrian, Kossiakoff Anthony, and Noinaj Nicholas
, Structure, 2023 Mar 17, (2023)
Nuclear pores. Architecture of the nuclear pore complex coat,
Stuwe, T., Correia A. R., Lin D. H., Paduch M., Lu V. T., Kossiakoff A. A., and Hoelz A.
, Science, 03/2015, Volume 347, Number 6226, p.1148-52, (2015)
Architecture of the fungal nuclear pore inner ring complex.,
Stuwe, Tobias, Bley Christopher J., Thierbach Karsten, Petrovic Stefan, Schilbach Sandra, Mayo Daniel J., Perriches Thibaud, Rundlet Emily J., Jeon Young E., Collins Leslie N., et al.
, Science, 2015 Oct 02, Volume 350, Issue 6256, p.56-64, (2015)
Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.,
Sun, Jian, Paduch Marcin, Kim Sang-Ah, Kramer Ryan M., Barrios Adam F., Lu Vincent, Luke Judy, Usatyuk Svitlana, Kossiakoff Anthony A., and Tan Song
, Proc Natl Acad Sci U S A, 2018 10 02, Volume 115, Issue 40, p.10010-10015, (2018)
Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity.,
Sundaram, Karthik M., Zhang Yilin, Mitra Anirban K., Kouadio Jean-Louis K., Gwin Katja, Kossiakoff Anthony A., Roman Brian B., Lengyel Ernst, and Piccirilli Joseph A.
, Cancer Res, 2017 Apr 01, Volume 77, Issue 7, p.1684-1696, (2017)
Publications
- Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.
- Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
- Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
- Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
- Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
- Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
- Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.
- Structure of an AMPK complex in an inactive, ATP-bound state.
- Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.
- Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
- Structures of ABCB4 provide insight into phosphatidylcholine translocation.
- Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
- Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.
- Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.