Publications
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Determination of equilibrium dissociation constants for recombinant antibodies by high-throughput affinity electrophoresis.,
Pan, Yuchen, Sackmann Eric K., Wypisniak Karolina, Hornsby Michael, Datwani Sammy S., and Herr Amy E.
, Sci Rep, 2016 Dec 23, Volume 6, p.39774, (2016)
O
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.,
Orlando, Benjamin J., Dominik Pawel K., Roy Sourav, Ogbu Chinemerem P., Erramilli Satchal K., Kossiakoff Anthony A., and Vecchio Alex J.
, J Biol Chem, 2022 Sep, Volume 298, Issue 9, p.102357, (2022)
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Direct Proximity Tagging of Small Molecule Protein Targets Using an Engineered NEDD8 Ligase.,
Hill, Zachary B., Pollock Samuel B., Zhuang Min, and Wells James A.
, J Am Chem Soc, 2016 Oct 12, Volume 138, Issue 40, p.13123-13126, (2016)
D
Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.,
Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al.
, Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)
B
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.,
Bloch, Joël S., Mukherjee Somnath, Kowal Julia, Filippova Ekaterina V., Niederer Martina, Pardon Els, Steyaert Jan, Kossiakoff Anthony A., and Locher Kaspar P.
, Proc Natl Acad Sci U S A, 2021 Nov 23, Volume 118, Issue 47, (2021)
Publications
- Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.
- Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
- Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
- Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
- Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
- Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
- Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.
- Structure of an AMPK complex in an inactive, ATP-bound state.
- Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.
- Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
- Structures of ABCB4 provide insight into phosphatidylcholine translocation.
- Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
- Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.
- Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.