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Filters: Author is Paduch, M. [Clear All Filters]

2012

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of gamma-secretase using synthetic antibodies, Zhang, X., Hoey R. J., Lin G., Koide A., Leung B., Ahn K., Dolios G., Paduch M., Ikeuchi T., Wang R., et al. , Proc Natl Acad Sci U S A, Volume 109, Number 22, p.8534-9, (2012)

Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo, Rizk, S. S., Misiura A., Paduch M., and Kossiakoff A. A. , Bioconjug Chem, Volume 23, Number 1, p.42-6, (2012)

2013

Generating conformation-specific synthetic antibodies to trap proteins in selected functional states, Paduch, M., Koide A., Uysal S., Rizk S. S., Koide S., and Kossiakoff A. A. , Methods, Volume 60, Number 1, p.3-14, (2013)

Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide, Shukla, A. K., Manglik A., Kruse A. C., Xiao K., Reis R. I., Tseng W. C., Staus D. P., Hilger D., Uysal S., Huang L. Y., et al. , Nature, Volume 497, Number 7447, p.137-41, (2013)

2014

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation, Marcon, E., Ni Z., Pu S., Turinsky A. L., Trimble S. S., Olsen J. B., Silverman-Gavrila R., Silverman-Gavrila L., Phanse S., Guo H., et al. , Cell Rep, Volume 8, Number 1, p.297-310, (2014)

Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies, Welch, B. D., Paduch M., Leser G. P., Bergman Z., Kors C. A., Paterson R. G., Jardetzky T. S., Kossiakoff A. A., and Lamb R. A. , J Virol, Volume 88, Number 20, p.11713-25, (2014)

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain, Li, Q., Wanderling S., Paduch M., Medovoy D., Singharoy A., McGreevy R., Villalba-Galea C. A., Hulse R. E., Roux B., Schulten K., et al. , Nat Struct Mol Biol, Volume 21, Number 3, p.244-52, (2014)

A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of gamma-secretase, Zhang, X., Hoey R., Koide A., Dolios G., Paduch M., Nguyen P., Wu X., Li Y., Wagner S. L., Wang R., et al. , J Biol Chem, Volume 289, Number 50, p.34851-61, (2014)

2015

Nuclear pores. Architecture of the nuclear pore complex coat, Stuwe, T., Correia A. R., Lin D. H., Paduch M., Lu V. T., Kossiakoff A. A., and Hoelz A. , Science, 03/2015, Volume 347, Number 6226, p.1148-52, (2015)

Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo, Mateja, A., Paduch M., Chang H. Y., Szydlowska A., Kossiakoff A. A., Hegde R. S., and Keenan R. J. , Science, 03/2015, Volume 347, Number 6226, p.1152-5, (2015)

Scalable high throughput selection from phage-displayed synthetic antibody libraries, Miersch, S., Li Z., Hanna R., McLaughlin M. E., Hornsby M., Matsuguchi T., Paduch M., Saaf A., Wells J., Koide S., et al. , J Vis Exp, 01/2015, Number 95, p.51492, (2015)