Publications
I
Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.,
Kordon, Szymon P., Dutka Przemysław, Adamska Justyna M., Bandekar Sumit J., Leon Katherine, Erramilli Satchal K., Adams Brock, Li Jingxian, Kossiakoff Anthony A., and Araç Demet
, Nat Commun, 2023 Feb 06, Volume 14, Issue 1, p.635, (2023)
Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.,
Kordon, Szymon P., Dutka Przemysław, Adamska Justyna M., Bandekar Sumit J., Leon Katherine, Erramilli Satchal K., Adams Brock, Li Jingxian, Kossiakoff Anthony A., and Araç Demet
, Nat Commun, 2023 Feb 06, Volume 14, Issue 1, p.635, (2023)
K
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.,
Yu, Yuanyuan, Zheng Qingyun, Erramilli Satchal K., Pan Man, Park Seongjin, Xie Yuan, Li Jingxian, Fei Jingyi, Kossiakoff Anthony A., Liu Lei, et al.
, Nat Chem Biol, 2021 Jul 08, (2021)
L
Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.,
Bailey, Lucas J., Sheehy Kimberly M., Dominik Pawel K., Liang Wenguang G., Rui Huan, Clark Michael, Jaskolowski Mateusz, Kim Yejoon, Deneka Dawid, Tang Wei-Jen, et al.
, J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)
Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.,
Bailey, Lucas J., Sheehy Kimberly M., Dominik Pawel K., Liang Wenguang G., Rui Huan, Clark Michael, Jaskolowski Mateusz, Kim Yejoon, Deneka Dawid, Tang Wei-Jen, et al.
, J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)
N
Nuclear pores. Architecture of the nuclear pore complex coat,
Stuwe, T., Correia A. R., Lin D. H., Paduch M., Lu V. T., Kossiakoff A. A., and Hoelz A.
, Science, 03/2015, Volume 347, Number 6226, p.1148-52, (2015)
O
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.,
Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al.
, PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.,
Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al.
, PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.,
Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al.
, PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)
P
A polar ring endows improved specificity to an antibody fragment.,
Schaefer, Zachary P., Bailey Lucas J., and Kossiakoff Anthony A.
, Protein Sci, 2016 07, Volume 25, Issue 7, p.1290-8, (2016)
The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.,
Galilee, Meytal, Britan-Rosich Elena, Griner Sarah L., Uysal Serdar, Baumgärtel Viola, Lamb Don C., Kossiakoff Anthony A., Kotler Moshe, Stroud Robert M., Marx Ailie, et al.
, Structure, 2016 11 01, Volume 24, Issue 11, p.1936-1946, (2016)
The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.,
Galilee, Meytal, Britan-Rosich Elena, Griner Sarah L., Uysal Serdar, Baumgärtel Viola, Lamb Don C., Kossiakoff Anthony A., Kotler Moshe, Stroud Robert M., Marx Ailie, et al.
, Structure, 2016 11 01, Volume 24, Issue 11, p.1936-1946, (2016)
Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies,
Welch, B. D., Paduch M., Leser G. P., Bergman Z., Kors C. A., Paterson R. G., Jardetzky T. S., Kossiakoff A. A., and Lamb R. A.
, J Virol, Volume 88, Number 20, p.11713-25, (2014)
Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies,
Welch, B. D., Paduch M., Leser G. P., Bergman Z., Kors C. A., Paterson R. G., Jardetzky T. S., Kossiakoff A. A., and Lamb R. A.
, J Virol, Volume 88, Number 20, p.11713-25, (2014)
Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity.,
Sundaram, Karthik M., Zhang Yilin, Mitra Anirban K., Kouadio Jean-Louis K., Gwin Katja, Kossiakoff Anthony A., Roman Brian B., Lengyel Ernst, and Piccirilli Joseph A.
, Cancer Res, 2017 Apr 01, Volume 77, Issue 7, p.1684-1696, (2017)
Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity.,
Sundaram, Karthik M., Zhang Yilin, Mitra Anirban K., Kouadio Jean-Louis K., Gwin Katja, Kossiakoff Anthony A., Roman Brian B., Lengyel Ernst, and Piccirilli Joseph A.
, Cancer Res, 2017 Apr 01, Volume 77, Issue 7, p.1684-1696, (2017)
Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo,
Mateja, A., Paduch M., Chang H. Y., Szydlowska A., Kossiakoff A. A., Hegde R. S., and Keenan R. J.
, Science, 03/2015, Volume 347, Number 6226, p.1152-5, (2015)
Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo,
Mateja, A., Paduch M., Chang H. Y., Szydlowska A., Kossiakoff A. A., Hegde R. S., and Keenan R. J.
, Science, 03/2015, Volume 347, Number 6226, p.1152-5, (2015)
Q
Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.,
Arrigoni, Cristina, Lolicato Marco, Shaya David, Rohaim Ahmed, Findeisen Felix, Fong Lam-Kiu, Colleran Claire M., Dominik Pawel, Kim Sangwoo S., Schuermann Jonathan P., et al.
, Nat Struct Mol Biol, 2022 Jun, Volume 29, Issue 6, p.537-548, (2022)
Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.,
Arrigoni, Cristina, Lolicato Marco, Shaya David, Rohaim Ahmed, Findeisen Felix, Fong Lam-Kiu, Colleran Claire M., Dominik Pawel, Kim Sangwoo S., Schuermann Jonathan P., et al.
, Nat Struct Mol Biol, 2022 Jun, Volume 29, Issue 6, p.537-548, (2022)
R
Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin.,
Farcasanu, Mara, Wang Andrew G., Uchański Tomasz, Bailey Lucas J., Yue Jiping, Chen Zhaochun, Wu Xiaoyang, Kossiakoff Anthony, and Tang Wei-Jen
, Biochemistry, 2019 07 09, Volume 58, Issue 27, p.2996-3004, (2019)
Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment.,
Lokareddy, Ravi K., Ko Ying Hui, Hong Nathaniel, Doll Steven G., Paduch Marcin, Niederweis Michael, Kossiakoff Anthony A., and Cingolani Gino
, Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)
Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment.,
Lokareddy, Ravi K., Ko Ying Hui, Hong Nathaniel, Doll Steven G., Paduch Marcin, Niederweis Michael, Kossiakoff Anthony A., and Cingolani Gino
, Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)
S
Scalable high throughput selection from phage-displayed synthetic antibody libraries,
Miersch, S., Li Z., Hanna R., McLaughlin M. E., Hornsby M., Matsuguchi T., Paduch M., Saaf A., Wells J., Koide S., et al.
, J Vis Exp, 01/2015, Number 95, p.51492, (2015)
Scalable high throughput selection from phage-displayed synthetic antibody libraries,
Miersch, S., Li Z., Hanna R., McLaughlin M. E., Hornsby M., Matsuguchi T., Paduch M., Saaf A., Wells J., Koide S., et al.
, J Vis Exp, 01/2015, Number 95, p.51492, (2015)
Pages
Publications
- Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.
- Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
- Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
- Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
- Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
- Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
- Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.
- Structure of an AMPK complex in an inactive, ATP-bound state.
- Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.
- Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
- Structures of ABCB4 provide insight into phosphatidylcholine translocation.
- Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
- Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.
- Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.