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2012

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of gamma-secretase using synthetic antibodies, Zhang, X., Hoey R. J., Lin G., Koide A., Leung B., Ahn K., Dolios G., Paduch M., Ikeuchi T., Wang R., et al. , Proc Natl Acad Sci U S A, Volume 109, Number 22, p.8534-9, (2012)

Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo, Rizk, S. S., Misiura A., Paduch M., and Kossiakoff A. A. , Bioconjug Chem, Volume 23, Number 1, p.42-6, (2012)

2013

Biomolecular Forms and Functions: A Celebration of 50 Years of the Ramachandran Map, Bansal, M., and Srinivasan N. , (2013)

CDR-H3 diversity is not required for antigen recognition by synthetic antibodies, Persson, H., Ye W., Wernimont A., Adams J. J., Koide A., Koide S., Lam R., and Sidhu S. S. , J Mol Biol, Volume 425, Number 4, p.803-11, (2013)

Generating conformation-specific synthetic antibodies to trap proteins in selected functional states, Paduch, M., Koide A., Uysal S., Rizk S. S., Koide S., and Kossiakoff A. A. , Methods, Volume 60, Number 1, p.3-14, (2013)

Structural Modeling of Human Growth Hormone Receptor using Computational Simulations and NMR Spectroscopy, Rui, H., Kossiakoff A., and Im W. , Biophys J, Volume 104, Number 2, Supplement 1, p.117a-118a, (2013)

Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide, Shukla, A. K., Manglik A., Kruse A. C., Xiao K., Reis R. I., Tseng W. C., Staus D. P., Hilger D., Uysal S., Huang L. Y., et al. , Nature, Volume 497, Number 7447, p.137-41, (2013)

2014

Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments, Bailey, L. J., Sheehy K. M., Hoey R. J., Schaefer Z. P., Ura M., and Kossiakoff A. A. , J Immunol Methods, Volume 415, p.24-30, (2014)

Cell biology. New tricks for an old dimer, Wells, J. A., and Kossiakoff A. A. , Science, Volume 344, Number 6185, p.703-4, (2014)

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation, Marcon, E., Ni Z., Pu S., Turinsky A. L., Trimble S. S., Olsen J. B., Silverman-Gavrila R., Silverman-Gavrila L., Phanse S., Guo H., et al. , Cell Rep, Volume 8, Number 1, p.297-310, (2014)

Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies, Welch, B. D., Paduch M., Leser G. P., Bergman Z., Kors C. A., Paterson R. G., Jardetzky T. S., Kossiakoff A. A., and Lamb R. A. , J Virol, Volume 88, Number 20, p.11713-25, (2014)

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain, Li, Q., Wanderling S., Paduch M., Medovoy D., Singharoy A., McGreevy R., Villalba-Galea C. A., Hulse R. E., Roux B., Schulten K., et al. , Nat Struct Mol Biol, Volume 21, Number 3, p.244-52, (2014)

A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of gamma-secretase, Zhang, X., Hoey R., Koide A., Dolios G., Paduch M., Nguyen P., Wu X., Li Y., Wagner S. L., Wang R., et al. , J Biol Chem, Volume 289, Number 50, p.34851-61, (2014)

Visualization of arrestin recruitment by a G-protein-coupled receptor, Shukla, A. K., Westfield G. H., Xiao K., Reis R. I., Huang L. Y., Tripathi-Shukla P., Qian J., Li S., Blanc A., Oleskie A. N., et al. , Nature, Volume 512, Number 7513, p.218-22, (2014)

2015

Architecture of the fungal nuclear pore inner ring complex., Stuwe, Tobias, Bley Christopher J., Thierbach Karsten, Petrovic Stefan, Schilbach Sandra, Mayo Daniel J., Perriches Thibaud, Rundlet Emily J., Jeon Young E., Collins Leslie N., et al. , Science, 2015 Oct 02, Volume 350, Issue 6256, p.56-64, (2015)

Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation., Marcon, Edyta, Jain Harshika, Bhattacharya Anandi, Guo Hongbo, Phanse Sadhna, Pu Shuye, Byram Gregory, Collins Ben C., Dowdell Evan, Fenner Maria, et al. , Nat Methods, 2015 Aug, Volume 12, Issue 8, p.725-31, (2015)

Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling, Rizk, S. S., Kouadio J. L., Szymborska A., Duguid E. M., Mukherjee S., Zheng J., Clevenger C. V., and Kossiakoff A. A. , Cell Commun Signal, 01/2015, Volume 13, Number 1, p.1, (2015)

A High Through-put Platform for Recombinant Antibodies to Folded Proteins., Hornsby, Michael, Paduch Marcin, Miersch Shane, Sääf Annika, Matsuguchi Tet, Lee Brian, Wypisniak Karolina, Doak Allison, King Daniel, Usatyuk Svitlana, et al. , Mol Cell Proteomics, 2015 Oct, Volume 14, Issue 10, p.2833-47, (2015)

An improved single-chain Fab platform for efficient display and recombinant expression., Koerber, James T., Hornsby Michael J., and Wells James A. , J Mol Biol, 2015 Jan 30, Volume 427, Issue 2, p.576-86, (2015)

Nuclear pores. Architecture of the nuclear pore complex coat, Stuwe, T., Correia A. R., Lin D. H., Paduch M., Lu V. T., Kossiakoff A. A., and Hoelz A. , Science, 03/2015, Volume 347, Number 6226, p.1148-52, (2015)

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins., Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al. , PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)

Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo, Mateja, A., Paduch M., Chang H. Y., Szydlowska A., Kossiakoff A. A., Hegde R. S., and Keenan R. J. , Science, 03/2015, Volume 347, Number 6226, p.1152-5, (2015)

Scalable high throughput selection from phage-displayed synthetic antibody libraries, Miersch, S., Li Z., Hanna R., McLaughlin M. E., Hornsby M., Matsuguchi T., Paduch M., Saaf A., Wells J., Koide S., et al. , J Vis Exp, 01/2015, Number 95, p.51492, (2015)

Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display., Huang, Haiming, Economopoulos Nicolas O., Liu Bernard A., Uetrecht Andrea, Gu Jun, Jarvik Nick, Nadeem Vincent, Pawson Tony, Moffat Jason, Miersch Shane, et al. , Protein Sci, 2015 Nov, Volume 24, Issue 11, p.1890-900, (2015)

A switchable yeast display/secretion system., Van Deventer, James A., Kelly Ryan L., Rajan Saravanan, K Wittrup Dane, and Sidhu Sachdev S. , Protein Eng Des Sel, 2015 Oct, Volume 28, Issue 10, p.317-25, (2015)

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