Publications
] Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.,
, Structure, 2023 Mar 17, (2023)
Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.,
, J Mol Biol, 2023 Jul 01, Volume 435, Issue 17, p.168192, (2023)
Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.,
, Nat Commun, 2023 Feb 06, Volume 14, Issue 1, p.635, (2023)
Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.,
, Nat Struct Mol Biol, 2023 Mar 16, (2023)
Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.,
, Nat Chem Biol, 2023 Jan 05, (2023)
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.,
, J Biol Chem, 2022 Sep, Volume 298, Issue 9, p.102357, (2022)
Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.,
, J Gen Physiol, 2022 Apr 04, Volume 154, Issue 4, (2022)
Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.,
, Nat Struct Mol Biol, 2022 Jun, Volume 29, Issue 6, p.537-548, (2022)
Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.,
, Cell Res, 2022 Aug, Volume 32, Issue 8, p.773-776, (2022)
Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.,
, Sci Adv, 2022 Jul 15, Volume 8, Issue 28, p.eabn8063, (2022)
Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.,
, J Mol Biol, 2022 Jun 30, Volume 434, Issue 12, p.167602, (2022)
Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.,
, J Clin Invest, 2022 Feb 15, Volume 132, Issue 4, (2022)
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.,
, Proc Natl Acad Sci U S A, 2021 Nov 23, Volume 118, Issue 47, (2021)
Engineered ultra-high affinity synthetic antibodies for SARS-CoV-2 neutralization and detection.,
, J Mol Biol, 2021 Mar 25, p.166956, (2021)
Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins.,
, J Mol Biol, 2021 Jun 04, Volume 433, Issue 15, p.167090, (2021)
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.,
, Nat Chem Biol, 2021 Jul 08, (2021)
Structural basis of omega-3 fatty acid transport across the blood-brain barrier.,
, Nature, 2021 Jun 16, (2021)
Structure of an AMPK complex in an inactive, ATP-bound state.,
, Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)
Structures of ABCB4 provide insight into phosphatidylcholine translocation.,
, Proc Natl Acad Sci U S A, 2021 Aug 17, Volume 118, Issue 33, (2021)
Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.,
, Nature, 2021 Jul 14, (2021)
A T cell redirection platform for co-targeting dual antigens on solid tumors.,
, MAbs, 2021 Jan-Dec, Volume 13, Issue 1, p.1933690, (2021)
An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.,
, Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)
Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment.,
, Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)
Structure and mechanism of the ER-based glucosyltransferase ALG6.,
, Nature, 03/2020, Volume 579, Issue 7799, p.443-447, (2020)
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling.,
, Elife, August 7 2020, Volume 9, (2020)
