Found 76 results
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Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes., Orlando, Benjamin J., Dominik Pawel K., Roy Sourav, Ogbu Chinemerem P., Erramilli Satchal K., Kossiakoff Anthony A., and Vecchio Alex J. , J Biol Chem, 2022 Sep, Volume 298, Issue 9, p.102357, (2022)
Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels., Rohaim, Ahmed, Slezak Tomasz, Koh Young Hoon, Blachowicz Lydia, Kossiakoff Anthony A., and Roux Benoît , J Gen Physiol, 2022 Apr 04, Volume 154, Issue 4, (2022)
Quaternary structure independent folding of voltage-gated ion channel pore domain subunits., Arrigoni, Cristina, Lolicato Marco, Shaya David, Rohaim Ahmed, Findeisen Felix, Fong Lam-Kiu, Colleran Claire M., Dominik Pawel, Kim Sangwoo S., Schuermann Jonathan P., et al. , Nat Struct Mol Biol, 2022 Jun, Volume 29, Issue 6, p.537-548, (2022)
Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver., Liu, Hongtao, Irobalieva Rossitza N., Bang-Sørensen Rose, Nosol Kamil, Mukherjee Somnath, Agrawal Parth, Stieger Bruno, Kossiakoff Anthony A., and Locher Kaspar P. , Cell Res, 2022 Aug, Volume 32, Issue 8, p.773-776, (2022)
Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias., Yen, Yu-Chen, Schafer Christopher T., Gustavsson Martin, Eberle Stefanie A., Dominik Pawel K., Deneka Dawid, Zhang Penglie, Schall Thomas J., Kossiakoff Anthony A., Tesmer John J. G., et al. , Sci Adv, 2022 Jul 15, Volume 8, Issue 28, p.eabn8063, (2022)
Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins., Ura, Marcin, Mukherjee Somnath, Marcon Edyta, Koestler Stefan A., and Kossiakoff Anthony A. , J Mol Biol, 2022 Jun 30, Volume 434, Issue 12, p.167602, (2022)
Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers., Lim, Shion A., Zhou Jie, Martinko Alexander J., Wang Yung-Hua, Filippova Ekaterina V., Steri Veronica, Wang Donghui, Remesh Soumya G., Liu Jia, Hann Byron, et al. , J Clin Invest, 2022 Feb 15, Volume 132, Issue 4, (2022)
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins., Bloch, Joël S., Mukherjee Somnath, Kowal Julia, Filippova Ekaterina V., Niederer Martina, Pardon Els, Steyaert Jan, Kossiakoff Anthony A., and Locher Kaspar P. , Proc Natl Acad Sci U S A, 2021 Nov 23, Volume 118, Issue 47, (2021)
Engineered ultra-high affinity synthetic antibodies for SARS-CoV-2 neutralization and detection., Slezak, Tomasz, and Kossiakoff Anthony A. , J Mol Biol, 2021 Mar 25, p.166956, (2021)
Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins., Gallo, Eugenio, Kelil Abdellali, Haughey Michael, Cazares-Olivera Mariana, Yates Bradley P., Zhang Mingjun, Wang Nai-Yu, Blazer Levi, Carderelli Lia, Adams Jarrett J., et al. , J Mol Biol, 2021 Jun 04, Volume 433, Issue 15, p.167090, (2021)
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle., Yu, Yuanyuan, Zheng Qingyun, Erramilli Satchal K., Pan Man, Park Seongjin, Xie Yuan, Li Jingxian, Fei Jingyi, Kossiakoff Anthony A., Liu Lei, et al. , Nat Chem Biol, 2021 Jul 08, (2021)
Structural basis of omega-3 fatty acid transport across the blood-brain barrier., Cater, Rosemary J., Chua Geok Lin, Erramilli Satchal K., Keener James E., Choy Brendon C., Tokarz Piotr, Chin Cheen Fei, Q Y Quek Debra, Kloss Brian, Pepe Joseph G., et al. , Nature, 2021 Jun 16, (2021)
Structure of an AMPK complex in an inactive, ATP-bound state., Yan, Yan, Mukherjee Somnath, Harikumar Kaleeckal G., Strutzenberg Timothy S., X Zhou Edward, Suino-Powell Kelly, Xu Ting-Hai, Sheldon Ryan D., Lamp Jared, Brunzelle Joseph S., et al. , Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)
Structures of ABCB4 provide insight into phosphatidylcholine translocation., Nosol, Kamil, Bang-Sørensen Rose, Irobalieva Rossitza N., Erramilli Satchal K., Stieger Bruno, Kossiakoff Anthony A., and Locher Kaspar P. , Proc Natl Acad Sci U S A, 2021 Aug 17, Volume 118, Issue 33, (2021)
Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1., Chen, Qiuyan, Plasencia Manolo, Li Zhuang, Mukherjee Somnath, Patra Dhabaleswar, Chen Chun-Liang, Klose Thomas, Yao Xin-Qiu, Kossiakoff Anthony A., Chang Leifu, et al. , Nature, 2021 Jul 14, (2021)
A T cell redirection platform for co-targeting dual antigens on solid tumors., Enderle, Leonie, Shalaby Karim H., Gorelik Maryna, Weiss Alexander, Blazer Levi L., Paduch Marcin, Cardarelli Lia, Kossiakoff Anthony, Adams Jarrett J., and Sidhu Sachdev S. , MAbs, 2021 Jan-Dec, Volume 13, Issue 1, p.1933690, (2021)
An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability., Slezak, Tomasz, Bailey Lucas J., Jaskolowski Mateusz, Nahotko Dominik A., Filippova Ekaterina V., Davydova Elena K., and Kossiakoff Anthony A. , Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)
Recognition of an α-helical hairpin in P22 large terminase by a synthetic antibody fragment., Lokareddy, Ravi K., Ko Ying Hui, Hong Nathaniel, Doll Steven G., Paduch Marcin, Niederweis Michael, Kossiakoff Anthony A., and Cingolani Gino , Acta Crystallogr D Struct Biol, September 1 2020, Volume 76, Issue Pt 9, p.876-888, (2020)
Structure and mechanism of the ER-based glucosyltransferase ALG6., Bloch, Joël S., Pesciullesi Giorgio, Boilevin Jérémy, Nosol Kamil, Irobalieva Rossitza N., Darbre Tamis, Aebi Markus, Kossiakoff Anthony A., Reymond Jean-Louis, and Locher Kaspar P. , Nature, 03/2020, Volume 579, Issue 7799, p.443-447, (2020)
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling., Tsutsumi, Naotaka, Mukherjee Somnath, Waghray Deepa, Janda Claudia Y., Jude Kevin M., Miao Yi, Burg John S., Aduri Nanda Gowtham, Kossiakoff Anthony A., Gati Cornelius, et al. , Elife, August 7 2020, Volume 9, (2020)
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins., Mukherjee, Somnath, Erramilli Satchal K., Ammirati Mark, Alvarez Frances J. D., Fennell Kimberly F., Purdy Michael D., Skrobek Blazej M., Radziwon Katarzyna, Coukos John, Kang Yanyong, et al. , Nat Commun, March 27 2020, Volume 11, Issue 1, p.1598, (2020)


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