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Z

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins., Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al. , PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of gamma-secretase using synthetic antibodies, Zhang, X., Hoey R. J., Lin G., Koide A., Leung B., Ahn K., Dolios G., Paduch M., Ikeuchi T., Wang R., et al. , Proc Natl Acad Sci U S A, Volume 109, Number 22, p.8534-9, (2012)

Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme., Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al. , Elife, 03/2018, Volume 7, (2018)

A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of gamma-secretase, Zhang, X., Hoey R., Koide A., Dolios G., Paduch M., Nguyen P., Wu X., Li Y., Wagner S. L., Wang R., et al. , J Biol Chem, Volume 289, Number 50, p.34851-61, (2014)

Y

K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle., Yu, Yuanyuan, Zheng Qingyun, Erramilli Satchal K., Pan Man, Park Seongjin, Xie Yuan, Li Jingxian, Fei Jingyi, Kossiakoff Anthony A., Liu Lei, et al. , Nat Chem Biol, 2021 Jul 08, (2021)

Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface., Ye, Xiaoying, Chan King C., Waters Andrew M., Bess Matthew, Harned Adam, Wei Bih-Rong, Loncarek Jadranka, Luke Brian T., Orsburn Benjamin C., Hollinger Bradley D., et al. , Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)

W

Cell biology. New tricks for an old dimer, Wells, J. A., and Kossiakoff A. A. , Science, Volume 344, Number 6185, p.703-4, (2014)

Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies, Welch, B. D., Paduch M., Leser G. P., Bergman Z., Kors C. A., Paterson R. G., Jardetzky T. S., Kossiakoff A. A., and Lamb R. A. , J Virol, Volume 88, Number 20, p.11713-25, (2014)

V

A switchable yeast display/secretion system., Van Deventer, James A., Kelly Ryan L., Rajan Saravanan, K Wittrup Dane, and Sidhu Sachdev S. , Protein Eng Des Sel, 2015 Oct, Volume 28, Issue 10, p.317-25, (2015)

T

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling., Tsutsumi, Naotaka, Mukherjee Somnath, Waghray Deepa, Janda Claudia Y., Jude Kevin M., Miao Yi, Burg John S., Aduri Nanda Gowtham, Kossiakoff Anthony A., Gati Cornelius, et al. , Elife, August 7 2020, Volume 9, (2020)

S

Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity., Sundaram, Karthik M., Zhang Yilin, Mitra Anirban K., Kouadio Jean-Louis K., Gwin Katja, Kossiakoff Anthony A., Roman Brian B., Lengyel Ernst, and Piccirilli Joseph A. , Cancer Res, 2017 Apr 01, Volume 77, Issue 7, p.1684-1696, (2017)

Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2., Sun, Jian, Paduch Marcin, Kim Sang-Ah, Kramer Ryan M., Barrios Adam F., Lu Vincent, Luke Judy, Usatyuk Svitlana, Kossiakoff Anthony A., and Tan Song , Proc Natl Acad Sci U S A, 2018 10 02, Volume 115, Issue 40, p.10010-10015, (2018)

Nuclear pores. Architecture of the nuclear pore complex coat, Stuwe, T., Correia A. R., Lin D. H., Paduch M., Lu V. T., Kossiakoff A. A., and Hoelz A. , Science, 03/2015, Volume 347, Number 6226, p.1148-52, (2015)

Architecture of the fungal nuclear pore inner ring complex., Stuwe, Tobias, Bley Christopher J., Thierbach Karsten, Petrovic Stefan, Schilbach Sandra, Mayo Daniel J., Perriches Thibaud, Rundlet Emily J., Jeon Young E., Collins Leslie N., et al. , Science, 2015 Oct 02, Volume 350, Issue 6256, p.56-64, (2015)

An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability., Slezak, Tomasz, Bailey Lucas J., Jaskolowski Mateusz, Nahotko Dominik A., Filippova Ekaterina V., Davydova Elena K., and Kossiakoff Anthony A. , Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)

Engineered ultra-high affinity synthetic antibodies for SARS-CoV-2 neutralization and detection., Slezak, Tomasz, and Kossiakoff Anthony A. , J Mol Biol, 2021 Mar 25, p.166956, (2021)

Visualization of arrestin recruitment by a G-protein-coupled receptor, Shukla, A. K., Westfield G. H., Xiao K., Reis R. I., Huang L. Y., Tripathi-Shukla P., Qian J., Li S., Blanc A., Oleskie A. N., et al. , Nature, Volume 512, Number 7513, p.218-22, (2014)

Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide, Shukla, A. K., Manglik A., Kruse A. C., Xiao K., Reis R. I., Tseng W. C., Staus D. P., Hilger D., Uysal S., Huang L. Y., et al. , Nature, Volume 497, Number 7447, p.137-41, (2013)

Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment., Shao, Yaming, Huang Hao, Qin Daoming, Li Nan-Sheng, Koide Akiko, Staley Jonathan P., Koide Shohei, Kossiakoff Anthony A., and Piccirilli Joseph A. , J Mol Biol, 2016 10 09, Volume 428, Issue 20, p.4100-4114, (2016)

A polar ring endows improved specificity to an antibody fragment., Schaefer, Zachary P., Bailey Lucas J., and Kossiakoff Anthony A. , Protein Sci, 2016 07, Volume 25, Issue 7, p.1290-8, (2016)

R

Structural Modeling of Human Growth Hormone Receptor using Computational Simulations and NMR Spectroscopy, Rui, H., Kossiakoff A., and Im W. , Biophys J, Volume 104, Number 2, Supplement 1, p.117a-118a, (2013)

Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo, Rizk, S. S., Misiura A., Paduch M., and Kossiakoff A. A. , Bioconjug Chem, Volume 23, Number 1, p.42-6, (2012)

Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling, Rizk, S. S., Kouadio J. L., Szymborska A., Duguid E. M., Mukherjee S., Zheng J., Clevenger C. V., and Kossiakoff A. A. , Cell Commun Signal, 01/2015, Volume 13, Number 1, p.1, (2015)

Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody., Rizk, Shahir S., Mukherjee Somnath, Koide Akiko, Koide Shohei, and Kossiakoff Anthony A. , Sci Rep, 2017 04 03, Volume 7, Issue 1, p.556, (2017)

The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab., Radwańska, Malwina J., Jaskółowski Mateusz, Davydova Elena, Derewenda Urszula, Miyake Tsuyoshi, Engel Daniel A., Kossiakoff Anthony A., and Derewenda Zygmunt S. , Acta Crystallogr D Struct Biol, 2018 07 01, Volume 74, Issue Pt 7, p.681-689, (2018)

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