Publications
2012
Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo,
Rizk, S. S., Misiura A., Paduch M., and Kossiakoff A. A.
, Bioconjug Chem, Volume 23, Number 1, p.42-6, (2012)
2013
Generating conformation-specific synthetic antibodies to trap proteins in selected functional states,
Paduch, M., Koide A., Uysal S., Rizk S. S., Koide S., and Kossiakoff A. A.
, Methods, Volume 60, Number 1, p.3-14, (2013)
Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide,
Shukla, A. K., Manglik A., Kruse A. C., Xiao K., Reis R. I., Tseng W. C., Staus D. P., Hilger D., Uysal S., Huang L. Y., et al.
, Nature, Volume 497, Number 7447, p.137-41, (2013)
2014
Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments,
Bailey, L. J., Sheehy K. M., Hoey R. J., Schaefer Z. P., Ura M., and Kossiakoff A. A.
, J Immunol Methods, Volume 415, p.24-30, (2014)
Cell biology. New tricks for an old dimer,
Wells, J. A., and Kossiakoff A. A.
, Science, Volume 344, Number 6185, p.703-4, (2014)
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation,
Marcon, E., Ni Z., Pu S., Turinsky A. L., Trimble S. S., Olsen J. B., Silverman-Gavrila R., Silverman-Gavrila L., Phanse S., Guo H., et al.
, Cell Rep, Volume 8, Number 1, p.297-310, (2014)
Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies,
Welch, B. D., Paduch M., Leser G. P., Bergman Z., Kors C. A., Paterson R. G., Jardetzky T. S., Kossiakoff A. A., and Lamb R. A.
, J Virol, Volume 88, Number 20, p.11713-25, (2014)
Visualization of arrestin recruitment by a G-protein-coupled receptor,
Shukla, A. K., Westfield G. H., Xiao K., Reis R. I., Huang L. Y., Tripathi-Shukla P., Qian J., Li S., Blanc A., Oleskie A. N., et al.
, Nature, Volume 512, Number 7513, p.218-22, (2014)
2015
Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling,
Rizk, S. S., Kouadio J. L., Szymborska A., Duguid E. M., Mukherjee S., Zheng J., Clevenger C. V., and Kossiakoff A. A.
, Cell Commun Signal, 01/2015, Volume 13, Number 1, p.1, (2015)
Nuclear pores. Architecture of the nuclear pore complex coat,
Stuwe, T., Correia A. R., Lin D. H., Paduch M., Lu V. T., Kossiakoff A. A., and Hoelz A.
, Science, 03/2015, Volume 347, Number 6226, p.1148-52, (2015)
Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo,
Mateja, A., Paduch M., Chang H. Y., Szydlowska A., Kossiakoff A. A., Hegde R. S., and Keenan R. J.
, Science, 03/2015, Volume 347, Number 6226, p.1152-5, (2015)