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234 entries « 12 of 12 »

Yang, Cindy F; Chiang, Michael C; Gray, Daniel C; Prabhakaran, Mahalakshmi; Alvarado, Maricruz; Juntti, Scott A; Unger, Elizabeth K; Wells, James A; Shah, Nirao M

Sexually dimorphic neurons in the ventromedial hypothalamus govern mating in both sexes and aggression in males Journal Article

In: Cell, vol. 153, no. 4, pp. 896–909, 2013, ISSN: 1097-4172.

Abstract | Links | BibTeX

Sexually dimorphic neurons in the ventromedial hypothalamus govern mating in both sexes and aggression in males

Thomsen, Nathan D; Koerber, James T; Wells, James A

Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation Journal Article

In: Proc Natl Acad Sci U S A, vol. 110, no. 21, pp. 8477–8482, 2013, ISSN: 1091-6490.

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Structural snapshots reveal distinct mechanisms of procaspase-3 and -7 activation

Datta, Debajyoti; McClendon, Christopher L; Jacobson, Matthew P; Wells, James A

Substrate and inhibitor-induced dimerization and cooperativity in caspase-1 but not caspase-3 Journal Article

In: J Biol Chem, vol. 288, no. 14, pp. 9971–9981, 2013, ISSN: 1083-351X.

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Substrate and inhibitor-induced dimerization and cooperativity in caspase-1 but not caspase-3

Paduch, Marcin; Koide, Akiko; Uysal, Serdar; Rizk, Shahir S; Koide, Shohei; Kossiakoff, Anthony A

Generating conformation-specific synthetic antibodies to trap proteins in selected functional states Journal Article

In: Methods, vol. 60, no. 1, pp. 3–14, 2013, ISSN: 1095-9130.

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Generating conformation-specific synthetic antibodies to trap proteins in selected functional states

Wang, Ningkun; Majmudar, Chinmay Y; Pomerantz, William C; Gagnon, Jessica K; Sadowsky, Jack D; Meagher, Jennifer L; Johnson, Taylor K; Stuckey, Jeanne A; Brooks, Charles L; Wells, James A; Mapp, Anna K

Ordering a dynamic protein via a small-molecule stabilizer Journal Article

In: J Am Chem Soc, vol. 135, no. 9, pp. 3363–3366, 2013, ISSN: 1520-5126.

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Ordering a dynamic protein via a small-molecule stabilizer

Crawford, Emily D; Seaman, Julia E; Agard, Nick; Hsu, Gerald W; Julien, Olivier; Mahrus, Sami; Nguyen, Huy; Shimbo, Kazutaka; Yoshihara, Hikari A I; Zhuang, Min; Chalkley, Robert J; Wells, James A

The DegraBase: a database of proteolysis in healthy and apoptotic human cells Journal Article

In: Mol Cell Proteomics, vol. 12, no. 3, pp. 813–824, 2013, ISSN: 1535-9484.

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The DegraBase: a database of proteolysis in healthy and apoptotic human cells

Persson, Helena; Ye, Wei; Wernimont, Amy; Adams, Jarrett J; Koide, Akiko; Koide, Shohei; Lam, Robert; Sidhu, Sachdev S

CDR-H3 diversity is not required for antigen recognition by synthetic antibodies Journal Article

In: J Mol Biol, vol. 425, no. 4, pp. 803–811, 2013, ISSN: 1089-8638.

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CDR-H3 diversity is not required for antigen recognition by synthetic antibodies

Zhuang, Min; Guan, Shenheng; Wang, Haopeng; Burlingame, Alma L; Wells, James A

Substrates of IAP ubiquitin ligases identified with a designed orthogonal E3 ligase, the NEDDylator Journal Article

In: Mol Cell, vol. 49, no. 2, pp. 273–282, 2013, ISSN: 1097-4164.

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Substrates of IAP ubiquitin ligases identified with a designed orthogonal E3 ligase, the NEDDylator

Crawford, E D; Seaman, J E; Barber, A E; David, D C; Babbitt, P C; Burlingame, A L; Wells, J A

Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis Journal Article

In: Cell Death Differ, vol. 19, no. 12, pp. 2040–2048, 2012, ISSN: 1476-5403.

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Conservation of caspase substrates across metazoans suggests hierarchical importance of signaling pathways over specific targets and cleavage site motifs in apoptosis

Zorn, Julie A; Wolan, Dennis W; Agard, Nicholas J; Wells, James A

Fibrils colocalize caspase-3 with procaspase-3 to foster maturation Journal Article

In: J Biol Chem, vol. 287, no. 40, pp. 33781–33795, 2012, ISSN: 1083-351X.

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Fibrils colocalize caspase-3 with procaspase-3 to foster maturation

Shimbo, Kazutaka; Hsu, Gerald W; Nguyen, Huy; Mahrus, Sami; Trinidad, Jonathan C; Burlingame, Alma L; Wells, James A

Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis Journal Article

In: Proc Natl Acad Sci U S A, vol. 109, no. 31, pp. 12432–12437, 2012, ISSN: 1091-6490.

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Quantitative profiling of caspase-cleaved substrates reveals different drug-induced and cell-type patterns in apoptosis

Zhang, Xulun; Hoey, Robert J; Lin, Guoqing; Koide, Akiko; Leung, Brenda; Ahn, Kwangwook; Dolios, Georgia; Paduch, Marcin; Ikeuchi, Takeshi; Wang, Rong; Li, Yue-Ming; Koide, Shohei; Sisodia, Sangram S

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies Journal Article

In: Proc Natl Acad Sci U S A, vol. 109, no. 22, pp. 8534–8539, 2012, ISSN: 1091-6490.

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Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies

Agard, Nicholas J; Mahrus, Sami; Trinidad, Jonathan C; Lynn, Aenoch; Burlingame, Alma L; Wells, James A

Global kinetic analysis of proteolysis via quantitative targeted proteomics Journal Article

In: Proc Natl Acad Sci U S A, vol. 109, no. 6, pp. 1913–1918, 2012, ISSN: 1091-6490.

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Global kinetic analysis of proteolysis via quantitative targeted proteomics

Rizk, Shahir S; Misiura, Agnieszka; Paduch, Marcin; Kossiakoff, Anthony A

Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo Journal Article

In: Bioconjug Chem, vol. 23, no. 1, pp. 42–46, 2012, ISSN: 1520-4812.

Abstract | Links | BibTeX

Substance P derivatives as versatile tools for specific delivery of various types of biomolecular cargo
234 entries « 12 of 12 »
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