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KDM8

Antigen Information

Antigen Gene Symbol: KDM8
Antigen Protein Name: lysine (K)-specific demethylase 8
Antigen Source Species: E. coli
Antigen Source Species ID: 562
Antigen Organism ID: 9606
Antigen Uniprot AC: Q8N371
Antigen Uniprot KB: KDM8_HUMAN
Antigen Species: Homo sapiens
Antigen Species ID: 9606

Binders

Binder Name: anti-KDM8-RAB-C331

Antigen Protein Domain and Sequence

Domain Name: TRX_family
Domain ID: 239245
Antigen Source Lab ID: FLJ13798A-A000
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 2
Antigen Protein Sequence: MHHHHHHSSGMSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLDANLAGTENLYFQSMAGDTHCPAEPLAREGTLWEALRALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGRRDECLQSSEVILDYSWEKLNTGTWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAALRVCDMGLLMGAAILGDILLKVAAILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS
Antigen Source Lab ID: FLJ13798A-A001
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 39
Antigen Protein Sequence: MSGLNDIFEAQKIEWHEGSAGGSGEKVERSVVTLLQRATELFYEGRRDECLQSSEVILDYSWEKLNTGTWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAALRVCDMGLLMGAAILGDILLKVAAILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWSGGSGHHHHHH
Antigen Source Lab ID: FLJ13798A-A002
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 179
Antigen Protein Sequence: MSGLNDIFEAQKIEWHEGSAGGSGKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWSGGSGHHHHHH
Antigen Source Lab ID: FLJ13798A-A150
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 180
Antigen Protein Sequence: MHHHHHHSSGVDLGTENLYFQSMLEKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS

Antigen Reference

Antigen Citation: 14702039; 15616553; 15489334; 20457893; 24981860; 24740926; 28455245; 28982940; 28847961; 30500822; 29563586; 29459673; 22851697; 24100311
BioGrid: 122923
ChiTaRS: KDM8
DMDM: 74728780
eggNOG: KOG2132
Ensembl: ENST00000286096 [Q8N371-1]; ENST00000441782 [Q8N371-3]; ENST00000568965 [Q8N371-2]
GeneCards: KDM8
GeneID: 79831
HOGENOME: CLU_016785_0_3_1
INPARANOID: Q8N371
IntAct: Q8N371
InterPro: IPR041667; IPR003347
KEGG: hsa:79831
MGI: MGI:1924285
MIM: 611917
OrthoDb: 1385616at2759
PDB: 3UYJ; 4AAP; 4GAZ; 4GJY; 4GJZ; 4QU1; 5FBJ; 6AVS; 6AX3; 6F4M; 6F4N; 6F4O; 6F4P; 6F4Q; 6F4R; 6F4S; 6F4T; 6I9L; 6I9M; 6I9N
PFAM: PF13621
PROSITE: PS51184
RefSeq: NP_001138820.1 [Q8N371-3]; NP_079049.2 [Q8N371-1]
SMART: SM00558
STRING: 9606.ENSP00000398410
TreeFam: TF315056
UCSC: uc002doh.3
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