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KDM6B

Antigen Information

Antigen Gene Symbol: KDM6B
Antigen Protein Name: lysine (K)-specific demethylase 6B
Antigen Source Species: E. coli
Antigen Source Species ID: 562
Antigen Organism ID: 9606
Antigen Uniprot AC: O15054
Antigen Uniprot KB: KDM6B_HUMAN
Antigen Species: Homo sapiens
Antigen Species ID: 9606

Binders

Binder Name: anti-KDM6B-RAB-C329
Binder Name: anti-KDM6B-RAB-C330

Antigen Protein Domain and Sequence

Domain Name: JmjC
Domain ID: 202224
Antigen Source Lab ID: JMJD3A-A001
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 1176
Antigen Protein Sequence: MHHHHHHSSGVDLGTENLYFQSMLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEV
Antigen Source Lab ID: JMJD3A-A002
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 1176
Antigen Protein Sequence: MHHHHHHSSGVDLGTENLYFQSMLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEV
Antigen Source Lab ID: JMJD3A-A003
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 1141
Antigen Protein Sequence: MHHHHHHSSGMSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLDANLAGTENLYFQSMDVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTS
Antigen Source Lab ID: JMJD3A-A005
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 1176
Antigen Protein Sequence: MSGLNDIFEAQKIEWHEGSAGGSGLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVGGSGHHHHHH
Antigen Source Lab ID: JMJD3A-A010
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 1170
Antigen Protein Sequence: MHHHHHHSSGVDLGTENLYFQSMINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLEQYRTEELAQAYDAFTLAPASTSR
Antigen Source Lab ID: JMJD3A-A025
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 1176
Antigen Protein Sequence: MHHHHHHSSGVDLGTENLYFQSMLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEV
Antigen Source Lab ID: JMJD3A-A037
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 1141
Antigen Protein Sequence: MHHHHHHSSGMSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKEFLDANLAGTENLYFQSMDVVRASRNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTGTPPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTS

Antigen Reference

Antigen Citation: 9205841; 12168954; 16625196; 15489334; 17193924; 17825402; 17851529; 17713478; 18003914; 23186163; 28262558; 28112733; 31124279
BioGrid: 116752
ChiTaRS: KDM6B
DIP: 59912
eggNOG: KOG1124; KOG1246
Ensembl: ENST00000254846 [O15054-1]; ENST00000448097 [O15054-2]
GeneCards: KDM6B
GeneID: 23135
HOGENOME: CLU_001909_0_0_1
INPARANOID: O15054
IntAct: O15054
InterPro: IPR003347; IPR029518
KEGG: hsa:23135
MGI: MGI:2448492
MIM: 611577; 618505
MINT: O15054
OrthoDb: 268901at2759
PDB: 2XUE; 2XXZ; 4ASK; 5FP3; 5OY3; 6F6D
PFAM: PF02373
PROSITE: PS51184
RefSeq: NP_001073893.1 [O15054-1]; NP_001335645.1 [O15054-2]; XP_005256606.1 [O15054-1]; XP_005256607.1 [O15054-1]; XP_005256608.1 [O15054-1]; XP_005256609.1 [O15054-1]; XP_006721546.1 [O15054-1]; XP_011522052.1 [O15054-1]; XP_011522054.1 [O15054-1]
SMART: SM00558
STRING: 9606.ENSP00000254846
TreeFam: TF317405
UCSC: uc002giw.2
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