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DNMT3A

Antigen Information

Antigen Gene Symbol: DNMT3A
Antigen Protein Name: DNA (cytosine-5-)-methyltransferase 3 alpha
Antigen Source Species: E. coli
Antigen Source Species ID: 562
Antigen Organism ID: 9606
Antigen Uniprot AC: Q9Y6K1
Antigen Uniprot KB: DNM3A_HUMAN
Antigen Species: Homo sapiens
Antigen Species ID: 9606

Binders

Binder Name: anti-DNMT3A-RAB-C311

Antigen Protein Domain and Sequence

Domain Name: Dnmt3b_related
Domain ID: 99896
Antigen Source Lab ID: DNMT3A-A003
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 278
Antigen Protein Sequence: MHHHHHHHHHHDLGTENLYFQSMGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEESSKGGYGLNDIFEAQKIEWHE
Antigen Source Lab ID: DNMT3A_11-A002
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 278
Antigen Protein Sequence: MHHHHHHHHHHDLGTENLYFQSMGDDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPKGLEPPEESSKGGYGLNDIFEAQKIEWHE

Antigen Reference

Antigen Citation: 10433969; 12138111; 12145218; 15815621; 15489334; 10325416; 17081983; 16682412; 16357870; 17200670; 18669648; 20871592; 21067377; 20068231; 21406692; 23186163; 24614070; 28112733; 30478443; 17713477; 19834512; 22086334; 21720545; 21828135; 27701732; 27317772; 27991732; 28941052; 28432085
BioGrid: 108125
ChiTaRS: DNMT3A
DIP: 38004
DMDM: 166215081
eggNOG: ENOG502QR6U
Ensembl: ENST00000264709 [Q9Y6K1-1]; ENST00000321117 [Q9Y6K1-1]; ENST00000380746 [Q9Y6K1-2]; ENST00000406659 [Q9Y6K1-3]
GeneCards: DNMT3A
GeneID: 1788
HOGENOME: CLU_121732_0_0_1
INPARANOID: Q9Y6K1
IntAct: Q9Y6K1
InterPro: IPR025766; IPR044108; IPR018117; IPR001525; IPR040552; IPR030487; IPR000313; IPR029063
KEGG: hsa:1788
MGI: MGI:1261827
MIM: 601626; 602769; 615879; 618724
MINT: Q9Y6K1
OrthoDb: 1015783at2759
PDB: 2QRV; 3A1A; 3A1B; 3LLR; 3SVM; 4QBQ; 4QBR; 4QBS; 4U7P; 4U7T; 5YX2; 6BRR; 6F57; 6PA7; 6W89; 6W8B; 6W8D; 6W8J
PFAM: PF17980; PF00145; PF00855
PROSITE: PS51533; PS00094; PS50812; PS51679
RefSeq: NP_001307821.1 [Q9Y6K1-3]; NP_001307822.1; NP_072046.2 [Q9Y6K1-1]; NP_715640.2 [Q9Y6K1-2]; NP_783328.1 [Q9Y6K1-1]; NP_783329.1 [Q9Y6K1-3]; XP_005264232.1 [Q9Y6K1-1]; XP_005264234.1; XP_011530969.1; XP_016859015.1 [Q9Y6K1-1]; XP_016859016.1
SMART: SM00293
STRING: 9606.ENSP00000264709
TreeFam: TF329039
UCSC: uc002rgb.5
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