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DNMT1

Antigen Information

Antigen Gene Symbol: DNMT1
Antigen Protein Name: DNA (cytosine-5-)-methyltransferase 1
Antigen Source Species: E. coli
Antigen Source Species ID: 562
Antigen Organism ID: 9606
Antigen Uniprot AC: P26358
Antigen Uniprot KB: DNMT1_HUMAN
Antigen Species: Homo sapiens
Antigen Species ID: 9606

Binders

Binder Name: anti-DNMT1-RAB-C310

Antigen Protein Domain and Sequence

Domain Name: DNMT1-RFD
Domain ID: 256817
Antigen Source Lab ID: DNMT1-A001
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 351
Antigen Protein Sequence: MHHHHHHHHHHDLGTENLYFQSMPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKESSKGGYGLNDIFEAQKIEWHE
Antigen Source Lab ID: DNMT1-A003
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 351
Antigen Protein Sequence: MHHHHHHHHHHDLGTENLYFQSMPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVSVIPSSKGGYGLNDIFEAQKIEWHE
Antigen Source Lab ID: DNMT1-A004
Antigen Source Lab: SGC
Antigen Protein Sequence Position: 351
Antigen Protein Sequence: MSGLNDIFEAQKIEWHEGSAGGSGPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKEGGSGHHHHHH

Antigen Reference

Antigen Citation: 1594447; 8940105; 15057824; 15489334; 10449766; 10753866; 9302295; 10947852; 10888872; 10888886; 10325416; 12145218; 17081983; 16357870; 17200670; 18754681; 18413740; 18220336; 18438403; 18669648; 19413330; 19450230; 19173286; 19690332; 19608861; 20068231; 21269460; 21565170; 21947282; 21151116; 21745816; 21406692; 23186163; 24623306; 24275569; 25772364; 28112733; 21389349; 21163962; 21532572; 22328086
BioGrid: 108123
ChiTaRS: DNMT1
DIP: 39693
DMDM: 12231019
eggNOG: ENOG502QPKK
Ensembl: ENST00000340748 [P26358-1]; ENST00000359526 [P26358-2]
GeneCards: DNMT1
GeneID: 1786
HOGENOME: CLU_003040_0_0_1
INPARANOID: P26358
IntAct: P26358
InterPro: IPR001025; IPR043151; IPR018117; IPR001525; IPR031303; IPR022702; IPR010506; IPR017198; IPR029063; IPR002857
KEGG: hsa:1786
MGI: MGI:94912
MIM: 126375; 604121; 614116
MINT: P26358
PDB: 3EPZ; 3PTA; 3SWR; 4WXX; 4YOC; 4Z96; 4Z97; 5WVO; 5YDR; 6K3A
PFAM: PF01426; PF06464; PF00145; PF12047; PF02008
PIR: S22610
PROSITE: PS51038; PS00094; PS00095; PS51912; PS51679; PS510
RefSeq: NP_001124295.1 [P26358-2]; NP_001305659.1; NP_001305660.1; NP_001370.1 [P26358-1]
SMART: SM00439; SM01137
STRING: 9606.ENSP00000352516
TreeFam: TF328926
UCSC: uc002mng.4
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