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2015

A High Through-put Platform for Recombinant Antibodies to Folded Proteins., Hornsby, Michael, Paduch Marcin, Miersch Shane, Sääf Annika, Matsuguchi Tet, Lee Brian, Wypisniak Karolina, Doak Allison, King Daniel, Usatyuk Svitlana, et al. , Mol Cell Proteomics, 2015 Oct, Volume 14, Issue 10, p.2833-47, (2015)

An improved single-chain Fab platform for efficient display and recombinant expression., Koerber, James T., Hornsby Michael J., and Wells James A. , J Mol Biol, 2015 Jan 30, Volume 427, Issue 2, p.576-86, (2015)

Nuclear pores. Architecture of the nuclear pore complex coat, Stuwe, T., Correia A. R., Lin D. H., Paduch M., Lu V. T., Kossiakoff A. A., and Hoelz A. , Science, 03/2015, Volume 347, Number 6226, p.1148-52, (2015)

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins., Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al. , PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins., Zhong, Nan, Loppnau Peter, Seitova Alma, Ravichandran Mani, Fenner Maria, Jain Harshika, Bhattacharya Anandi, Hutchinson Ashley, Paduch Marcin, Lu Vincent, et al. , PLoS One, 2015, Volume 10, Issue 10, p.e0139695, (2015)

Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo, Mateja, A., Paduch M., Chang H. Y., Szydlowska A., Kossiakoff A. A., Hegde R. S., and Keenan R. J. , Science, 03/2015, Volume 347, Number 6226, p.1152-5, (2015)

Scalable high throughput selection from phage-displayed synthetic antibody libraries, Miersch, S., Li Z., Hanna R., McLaughlin M. E., Hornsby M., Matsuguchi T., Paduch M., Saaf A., Wells J., Koide S., et al. , J Vis Exp, 01/2015, Number 95, p.51492, (2015)

Scalable high throughput selection from phage-displayed synthetic antibody libraries, Miersch, S., Li Z., Hanna R., McLaughlin M. E., Hornsby M., Matsuguchi T., Paduch M., Saaf A., Wells J., Koide S., et al. , J Vis Exp, 01/2015, Number 95, p.51492, (2015)

Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display., Huang, Haiming, Economopoulos Nicolas O., Liu Bernard A., Uetrecht Andrea, Gu Jun, Jarvik Nick, Nadeem Vincent, Pawson Tony, Moffat Jason, Miersch Shane, et al. , Protein Sci, 2015 Nov, Volume 24, Issue 11, p.1890-900, (2015)

2014

Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments, Bailey, L. J., Sheehy K. M., Hoey R. J., Schaefer Z. P., Ura M., and Kossiakoff A. A. , J Immunol Methods, Volume 415, p.24-30, (2014)

Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation, Marcon, E., Ni Z., Pu S., Turinsky A. L., Trimble S. S., Olsen J. B., Silverman-Gavrila R., Silverman-Gavrila L., Phanse S., Guo H., et al. , Cell Rep, Volume 8, Number 1, p.297-310, (2014)

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain, Li, Q., Wanderling S., Paduch M., Medovoy D., Singharoy A., McGreevy R., Villalba-Galea C. A., Hulse R. E., Roux B., Schulten K., et al. , Nat Struct Mol Biol, Volume 21, Number 3, p.244-52, (2014)

A synthetic antibody fragment targeting nicastrin affects assembly and trafficking of gamma-secretase, Zhang, X., Hoey R., Koide A., Dolios G., Paduch M., Nguyen P., Wu X., Li Y., Wagner S. L., Wang R., et al. , J Biol Chem, Volume 289, Number 50, p.34851-61, (2014)

Visualization of arrestin recruitment by a G-protein-coupled receptor, Shukla, A. K., Westfield G. H., Xiao K., Reis R. I., Huang L. Y., Tripathi-Shukla P., Qian J., Li S., Blanc A., Oleskie A. N., et al. , Nature, Volume 512, Number 7513, p.218-22, (2014)

Visualization of arrestin recruitment by a G-protein-coupled receptor, Shukla, A. K., Westfield G. H., Xiao K., Reis R. I., Huang L. Y., Tripathi-Shukla P., Qian J., Li S., Blanc A., Oleskie A. N., et al. , Nature, Volume 512, Number 7513, p.218-22, (2014)

2013

Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide, Shukla, A. K., Manglik A., Kruse A. C., Xiao K., Reis R. I., Tseng W. C., Staus D. P., Hilger D., Uysal S., Huang L. Y., et al. , Nature, Volume 497, Number 7447, p.137-41, (2013)

Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide, Shukla, A. K., Manglik A., Kruse A. C., Xiao K., Reis R. I., Tseng W. C., Staus D. P., Hilger D., Uysal S., Huang L. Y., et al. , Nature, Volume 497, Number 7447, p.137-41, (2013)

2012

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of gamma-secretase using synthetic antibodies, Zhang, X., Hoey R. J., Lin G., Koide A., Leung B., Ahn K., Dolios G., Paduch M., Ikeuchi T., Wang R., et al. , Proc Natl Acad Sci U S A, Volume 109, Number 22, p.8534-9, (2012)

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