Publications
] Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.,
, Nat Commun, 2023 Feb 06, Volume 14, Issue 1, p.635, (2023)
Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.,
, Nat Struct Mol Biol, 2023 Mar 16, (2023)
Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.,
, Nat Struct Mol Biol, 2023 Mar 16, (2023)
Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.,
, Nat Chem Biol, 2023 Jan 05, (2023)
Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.,
, Nat Chem Biol, 2023 Jan 05, (2023)
Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.,
, J Gen Physiol, 2022 Apr 04, Volume 154, Issue 4, (2022)
Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.,
, Cell Res, 2022 Aug, Volume 32, Issue 8, p.773-776, (2022)
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.,
, Proc Natl Acad Sci U S A, 2021 Nov 23, Volume 118, Issue 47, (2021)
Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins.,
, J Mol Biol, 2021 Jun 04, Volume 433, Issue 15, p.167090, (2021)
Structure of an AMPK complex in an inactive, ATP-bound state.,
, Science, 2021 Jul 23, Volume 373, Issue 6553, p.413-419, (2021)
Structures of ABCB4 provide insight into phosphatidylcholine translocation.,
, Proc Natl Acad Sci U S A, 2021 Aug 17, Volume 118, Issue 33, (2021)
A T cell redirection platform for co-targeting dual antigens on solid tumors.,
, MAbs, 2021 Jan-Dec, Volume 13, Issue 1, p.1933690, (2021)
An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability.,
, Protein Sci, 2020 01, Volume 29, Issue 1, p.141-156, (2020)
Structure and mechanism of the ER-based glucosyltransferase ALG6.,
, Nature, 03/2020, Volume 579, Issue 7799, p.443-447, (2020)
Structure and mechanism of the ER-based glucosyltransferase ALG6.,
, Nature, 03/2020, Volume 579, Issue 7799, p.443-447, (2020)
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling.,
, Elife, August 7 2020, Volume 9, (2020)
Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin.,
, Biochemistry, 2019 07 09, Volume 58, Issue 27, p.2996-3004, (2019)
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.,
, Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.,
, Elife, 03/2018, Volume 7, (2018)
Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.,
, J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)
Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.,
, Proc Natl Acad Sci U S A, 2018 10 02, Volume 115, Issue 40, p.10010-10015, (2018)
Structural basis for activation of voltage sensor domains in an ion channel TPC1.,
, Proc Natl Acad Sci U S A, 2018 09 25, Volume 115, Issue 39, p.E9095-E9104, (2018)
Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.,
, Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)
Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.,
, Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)
Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.,
, Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)
