Publications
A
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.,
Marcon, Edyta, Jain Harshika, Bhattacharya Anandi, Guo Hongbo, Phanse Sadhna, Pu Shuye, Byram Gregory, Collins Ben C., Dowdell Evan, Fenner Maria, et al.
, Nat Methods, 2015 Aug, Volume 12, Issue 8, p.725-31, (2015)
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.,
Marcon, Edyta, Jain Harshika, Bhattacharya Anandi, Guo Hongbo, Phanse Sadhna, Pu Shuye, Byram Gregory, Collins Ben C., Dowdell Evan, Fenner Maria, et al.
, Nat Methods, 2015 Aug, Volume 12, Issue 8, p.725-31, (2015)
C
CDR-H3 diversity is not required for antigen recognition by synthetic antibodies,
Persson, H., Ye W., Wernimont A., Adams J. J., Koide A., Koide S., Lam R., and Sidhu S. S.
, J Mol Biol, Volume 425, Number 4, p.803-11, (2013)
Cell biology. New tricks for an old dimer,
Wells, J. A., and Kossiakoff A. A.
, Science, Volume 344, Number 6185, p.703-4, (2014)
Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.,
Ye, Xiaoying, Chan King C., Waters Andrew M., Bess Matthew, Harned Adam, Wei Bih-Rong, Loncarek Jadranka, Luke Brian T., Orsburn Benjamin C., Hollinger Bradley D., et al.
, Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)
Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.,
Ye, Xiaoying, Chan King C., Waters Andrew M., Bess Matthew, Harned Adam, Wei Bih-Rong, Loncarek Jadranka, Luke Brian T., Orsburn Benjamin C., Hollinger Bradley D., et al.
, Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)
Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.,
Ye, Xiaoying, Chan King C., Waters Andrew M., Bess Matthew, Harned Adam, Wei Bih-Rong, Loncarek Jadranka, Luke Brian T., Orsburn Benjamin C., Hollinger Bradley D., et al.
, Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)
Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.,
Ye, Xiaoying, Chan King C., Waters Andrew M., Bess Matthew, Harned Adam, Wei Bih-Rong, Loncarek Jadranka, Luke Brian T., Orsburn Benjamin C., Hollinger Bradley D., et al.
, Oncotarget, 2016 Dec 27, Volume 7, Issue 52, p.86948-86971, (2016)
D
Determination of equilibrium dissociation constants for recombinant antibodies by high-throughput affinity electrophoresis.,
Pan, Yuchen, Sackmann Eric K., Wypisniak Karolina, Hornsby Michael, Datwani Sammy S., and Herr Amy E.
, Sci Rep, 2016 Dec 23, Volume 6, p.39774, (2016)
Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.,
Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al.
, Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)
Direct Proximity Tagging of Small Molecule Protein Targets Using an Engineered NEDD8 Ligase.,
Hill, Zachary B., Pollock Samuel B., Zhuang Min, and Wells James A.
, J Am Chem Soc, 2016 Oct 12, Volume 138, Issue 40, p.13123-13126, (2016)
E
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.,
Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al.
, Elife, 03/2018, Volume 7, (2018)
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.,
Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al.
, Elife, 03/2018, Volume 7, (2018)
Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.,
Zhang, Zhening, Liang Wenguang G., Bailey Lucas J., Tan Yong Zi, Wei Hui, Wang Andrew, Farcasanu Mara, Woods Virgil A., McCord Lauren A., Lee David, et al.
, Elife, 03/2018, Volume 7, (2018)
F
Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds.,
Liu, Hongyan, Saxena Abhishek, Sidhu Sachdev S., and Wu Donghui
, Front Immunol, 2017, Volume 8, p.38, (2017)
H
A High Through-put Platform for Recombinant Antibodies to Folded Proteins.,
Hornsby, Michael, Paduch Marcin, Miersch Shane, Sääf Annika, Matsuguchi Tet, Lee Brian, Wypisniak Karolina, Doak Allison, King Daniel, Usatyuk Svitlana, et al.
, Mol Cell Proteomics, 2015 Oct, Volume 14, Issue 10, p.2833-47, (2015)
A High Through-put Platform for Recombinant Antibodies to Folded Proteins.,
Hornsby, Michael, Paduch Marcin, Miersch Shane, Sääf Annika, Matsuguchi Tet, Lee Brian, Wypisniak Karolina, Doak Allison, King Daniel, Usatyuk Svitlana, et al.
, Mol Cell Proteomics, 2015 Oct, Volume 14, Issue 10, p.2833-47, (2015)
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.,
Pollock, Samuel B., Hu Amy, Mou Yun, Martinko Alexander J., Julien Olivier, Hornsby Michael, Ploder Lynda, Adams Jarrett J., Geng Huimin, Müschen Markus, et al.
, Proc Natl Acad Sci U S A, 2018 03 13, Volume 115, Issue 11, p.2836-2841, (2018)
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation,
Marcon, E., Ni Z., Pu S., Turinsky A. L., Trimble S. S., Olsen J. B., Silverman-Gavrila R., Silverman-Gavrila L., Phanse S., Guo H., et al.
, Cell Rep, Volume 8, Number 1, p.297-310, (2014)
I
Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of gamma-secretase using synthetic antibodies,
Zhang, X., Hoey R. J., Lin G., Koide A., Leung B., Ahn K., Dolios G., Paduch M., Ikeuchi T., Wang R., et al.
, Proc Natl Acad Sci U S A, Volume 109, Number 22, p.8534-9, (2012)
An improved single-chain Fab platform for efficient display and recombinant expression.,
Koerber, James T., Hornsby Michael J., and Wells James A.
, J Mol Biol, 2015 Jan 30, Volume 427, Issue 2, p.576-86, (2015)
Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins.,
Gallo, Eugenio, Kelil Abdellali, Haughey Michael, Cazares-Olivera Mariana, Yates Bradley P., Zhang Mingjun, Wang Nai-Yu, Blazer Levi, Carderelli Lia, Adams Jarrett J., et al.
, J Mol Biol, 2021 Jun 04, Volume 433, Issue 15, p.167090, (2021)
Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins.,
Gallo, Eugenio, Kelil Abdellali, Haughey Michael, Cazares-Olivera Mariana, Yates Bradley P., Zhang Mingjun, Wang Nai-Yu, Blazer Levi, Carderelli Lia, Adams Jarrett J., et al.
, J Mol Biol, 2021 Jun 04, Volume 433, Issue 15, p.167090, (2021)
P
Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies,
Welch, B. D., Paduch M., Leser G. P., Bergman Z., Kors C. A., Paterson R. G., Jardetzky T. S., Kossiakoff A. A., and Lamb R. A.
, J Virol, Volume 88, Number 20, p.11713-25, (2014)
R
Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin.,
Farcasanu, Mara, Wang Andrew G., Uchański Tomasz, Bailey Lucas J., Yue Jiping, Chen Zhaochun, Wu Xiaoyang, Kossiakoff Anthony, and Tang Wei-Jen
, Biochemistry, 2019 07 09, Volume 58, Issue 27, p.2996-3004, (2019)
Pages
Publications
- Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum.
- Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
- Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
- Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
- Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
- Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
- Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels.
- Structure of an AMPK complex in an inactive, ATP-bound state.
- Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.
- Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
- Structures of ABCB4 provide insight into phosphatidylcholine translocation.
- Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
- Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.
- Targeting a proteolytic neoepitope on CUB domain containing protein 1 (CDCP1) for RAS-driven cancers.