Publications
B
Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments,
Bailey, L. J., Sheehy K. M., Hoey R. J., Schaefer Z. P., Ura M., and Kossiakoff A. A.
, J Immunol Methods, Volume 415, p.24-30, (2014)
Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.,
Bailey, Lucas J., Sheehy Kimberly M., Dominik Pawel K., Liang Wenguang G., Rui Huan, Clark Michael, Jaskolowski Mateusz, Kim Yejoon, Deneka Dawid, Tang Wei-Jen, et al.
, J Mol Biol, 2018 02 02, Volume 430, Issue 3, p.337-347, (2018)
Biomolecular Forms and Functions: A Celebration of 50 Years of the Ramachandran Map,
Bansal, M., and Srinivasan N.
, (2013)
Structure and mechanism of the ER-based glucosyltransferase ALG6.,
Bloch, Joël S., Pesciullesi Giorgio, Boilevin Jérémy, Nosol Kamil, Irobalieva Rossitza N., Darbre Tamis, Aebi Markus, Kossiakoff Anthony A., Reymond Jean-Louis, and Locher Kaspar P.
, Nature, 03/2020, Volume 579, Issue 7799, p.443-447, (2020)
C
Structural basis of omega-3 fatty acid transport across the blood-brain barrier.,
Cater, Rosemary J., Chua Geok Lin, Erramilli Satchal K., Keener James E., Choy Brendon C., Tokarz Piotr, Chin Cheen Fei, Q Y Quek Debra, Kloss Brian, Pepe Joseph G., et al.
, Nature, 2021 Jun 16, (2021)
Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.,
Chen, Qiuyan, Plasencia Manolo, Li Zhuang, Mukherjee Somnath, Patra Dhabaleswar, Chen Chun-Liang, Klose Thomas, Yao Xin-Qiu, Kossiakoff Anthony A., Chang Leifu, et al.
, Nature, 2021 Jul 14, (2021)
Synthetic antibodies and peptides recognizing progressive multifocal leukoencephalopathy-specific point mutations in polyomavirus JC capsid viral protein 1.,
Chen, Gang, Gorelik Leonid, Simon Kenneth J., Pavlenco Alevtina, Cheung Anne, Brickelmaier Margot, Chen Ling Ling, Jin Ping, Weinreb Paul H., and Sidhu Sachdev S.
, MAbs, 2015, Volume 7, Issue 4, p.681-92, (2015)
D
Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs.,
Dominik, Pawel K., Borowska Marta T., Dalmas Olivier, Kim Sangwoo S., Perozo Eduardo, Keenan Robert J., and Kossiakoff Anthony A.
, Structure, 2016 Feb 02, Volume 24, Issue 2, p.300-9, (2016)
Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.,
Dutka, Przemyslaw, Mukherjee Somnath, Gao Xiang, Kang Yanyong, de Waal Parker W., Wang Lei, Zhuang Youwen, Melcher Karsten, Zhang Cheng, H Xu Eric, et al.
, Structure, 2019 12 03, Volume 27, Issue 12, p.1862-1874.e7, (2019)
E
A T cell redirection platform for co-targeting dual antigens on solid tumors.,
Enderle, Leonie, Shalaby Karim H., Gorelik Maryna, Weiss Alexander, Blazer Levi L., Paduch Marcin, Cardarelli Lia, Kossiakoff Anthony, Adams Jarrett J., and Sidhu Sachdev S.
, MAbs, 2021 Jan-Dec, Volume 13, Issue 1, p.1933690, (2021)
F
Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin.,
Farcasanu, Mara, Wang Andrew G., Uchański Tomasz, Bailey Lucas J., Yue Jiping, Chen Zhaochun, Wu Xiaoyang, Kossiakoff Anthony, and Tang Wei-Jen
, Biochemistry, 2019 07 09, Volume 58, Issue 27, p.2996-3004, (2019)
G
The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.,
Galilee, Meytal, Britan-Rosich Elena, Griner Sarah L., Uysal Serdar, Baumgärtel Viola, Lamb Don C., Kossiakoff Anthony A., Kotler Moshe, Stroud Robert M., Marx Ailie, et al.
, Structure, 2016 11 01, Volume 24, Issue 11, p.1936-1946, (2016)
Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on αv Integrins.,
Gallo, Eugenio, Kelil Abdellali, Haughey Michael, Cazares-Olivera Mariana, Yates Bradley P., Zhang Mingjun, Wang Nai-Yu, Blazer Levi, Carderelli Lia, Adams Jarrett J., et al.
, J Mol Biol, 2021 Jun 04, Volume 433, Issue 15, p.167090, (2021)
H
Direct Proximity Tagging of Small Molecule Protein Targets Using an Engineered NEDD8 Ligase.,
Hill, Zachary B., Pollock Samuel B., Zhuang Min, and Wells James A.
, J Am Chem Soc, 2016 Oct 12, Volume 138, Issue 40, p.13123-13126, (2016)
A High Through-put Platform for Recombinant Antibodies to Folded Proteins.,
Hornsby, Michael, Paduch Marcin, Miersch Shane, Sääf Annika, Matsuguchi Tet, Lee Brian, Wypisniak Karolina, Doak Allison, King Daniel, Usatyuk Svitlana, et al.
, Mol Cell Proteomics, 2015 Oct, Volume 14, Issue 10, p.2833-47, (2015)
Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain.,
Huang, Haiming, Kaneko Tomonori, Sidhu Sachdev S., and Li Shawn S. C.
, Methods Mol Biol, 2017, Volume 1555, p.225-254, (2017)
Selection of recombinant anti-SH3 domain antibodies by high-throughput phage display.,
Huang, Haiming, Economopoulos Nicolas O., Liu Bernard A., Uetrecht Andrea, Gu Jun, Jarvik Nick, Nadeem Vincent, Pawson Tony, Moffat Jason, Miersch Shane, et al.
, Protein Sci, 2015 Nov, Volume 24, Issue 11, p.1890-900, (2015)
K
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.,
Kang, Yanyong, Kuybeda Oleg, de Waal Parker W., Mukherjee Somnath, Van Eps Ned, Dutka Przemyslaw, X Zhou Edward, Bartesaghi Alberto, Erramilli Satchal, Morizumi Takefumi, et al.
, Nature, 2018 06, Volume 558, Issue 7711, p.553-558, (2018)
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.,
Kim, Jonathan, Tan Yong Zi, Wicht Kathryn J., Erramilli Satchal K., Dhingra Satish K., Okombo John, Vendome Jeremie, Hagenah Laura M., Giacometti Sabrina I., Warren Audrey L., et al.
, Nature, 2019 12, Volume 576, Issue 7786, p.315-320, (2019)
Structural basis for activation of voltage sensor domains in an ion channel TPC1.,
Kintzer, Alexander F., Green Evan M., Dominik Pawel K., Bridges Michael, Armache Jean-Paul, Deneka Dawid, Kim Sangwoo S., Hubbell Wayne, Kossiakoff Anthony A., Cheng Yifan, et al.
, Proc Natl Acad Sci U S A, 2018 09 25, Volume 115, Issue 39, p.E9095-E9104, (2018)
An improved single-chain Fab platform for efficient display and recombinant expression.,
Koerber, James T., Hornsby Michael J., and Wells James A.
, J Mol Biol, 2015 Jan 30, Volume 427, Issue 2, p.576-86, (2015)
L
A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents.,
Leung, Isabel, Jarvik Nick, and Sidhu Sachdev S.
, J Mol Biol, 2017 01 06, Volume 429, Issue 1, p.115-127, (2017)
Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain,
Li, Q., Wanderling S., Paduch M., Medovoy D., Singharoy A., McGreevy R., Villalba-Galea C. A., Hulse R. E., Roux B., Schulten K., et al.
, Nat Struct Mol Biol, Volume 21, Number 3, p.244-52, (2014)
Redox-based reagents for chemoselective methionine bioconjugation.,
Lin, Shixian, Yang Xiaoyu, Jia Shang, Weeks Amy M., Hornsby Michael, Lee Peter S., Nichiporuk Rita V., Iavarone Anthony T., Wells James A., F Toste Dean, et al.
, Science, 2017 02 10, Volume 355, Issue 6325, p.597-602, (2017)
Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds.,
Liu, Hongyan, Saxena Abhishek, Sidhu Sachdev S., and Wu Donghui
, Front Immunol, 2017, Volume 8, p.38, (2017)
Pages
RAN Publications
Latest publications
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Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. (published on 2021 Jul 14)
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K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle. (published on 2021 Jul 08)
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A T cell redirection platform for co-targeting dual antigens on solid tumors. (published on 2021 Jan-Dec)